City University of New York

Soterix Medical, Inc.

Shiraz Azar Macuff

Marom Bikson

Lucas Cristobal Parra

Abhishek Datta

Christoph Hahn

Preet Minhas

Niranjan Khadka

Justin Keith Rice

Asif Rahman

In some embodiments of the present disclosure, systems and methods for effecting a physiological effect are provided. In some embodiments, a system is provided which comprises a plurality of current sources, where each current source having a positive output and a negative output and each being configured to provide a first current. The system may also include a plurality of stimulating electrodes electrically connected with the plurality of current sources such that at least a pair of the stimulating electrodes share at least one output of at least one of the plurality of current sources. The stimulating electrodes may be configured to provide electrical energy to tissue of a patient at the first current. The system may further include at least one sentinel electrode, and a first voltage monitor configured to monitor a first voltage across the at least one sentinel electrode and at least one of the plurality of stimulating electrodes.

System and method for conducting multi-electrode electrical stimulation

Methods and systems for delivering voltage limited neurostimulation to a patient. In one aspect, a method includes initiating a flow of electrical current through a first electrode and a second electrode coupled to the patient and increasing the flow of electrical current toward a target value by increasing a voltage across the first electrode and second electrode. Prior to reaching the target value of electrical current, the method includes preventing the voltage across the first electrode and second electrode from increasing beyond a first predetermined limit; and subsequently, maintaining the voltage across the first electrode and second electrode at or within a predetermined range that does not exceed the first predetermined limit. The amplitude of the electrical current continues to increase toward the target value during at least part of a time when the voltage across the first electrode and the second electrode is maintained within the predetermined range.

Voltage limited neurostimulation

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Hollis, NY, United States of America

Shiraz Azar Macuff