Canon Kabushiki Kaisha

Shinzaburo Ito

Tetsuya Yano

Tatsuki Fukui

Masato Minami

Kengo Kanazaki

Hiroyuki Aoki

Atsushi Takahashi

Yoshinori Tomida

Satoshi Yuasa

Fumio Yamauchi

Satoshi Ogawa

Kouichi Kato

Daisuke Sasaguri

Fumiko Tomatsu

There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.

Particle and contrast agent having the particle

A particle includes a copolymer of lactic acid and glycolic acid, and at least one compound selected from silicon naphthalocyanine and derivatives of silicon naphthalocyanine, in which the particle has a particle size of 10 nm or more and less than 1000 nm.

Particles and contrast agent including the same for optical imaging

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Kyoto, Japan

Shinzaburo Ito