Toyo Boseki Kabushiki Kaisha

Shinya Koyama

Kimihiro Mabuchi

Katsuhiko Nose

Katsuaki Kuze

Noriko Monden

Hiroshi Shibano

Makoto Ohno

Hidehiko Sakurai

Isamu Yamamoto

Tohru Uenishi

Noriyuki Tamamura

Takahito Sagara

The present invention provides a hollow fiber membrane where the membrane strength and pressure resistance to pressurization from the dialysate side is ensured, the retaining rate of water permeability after the repeated pressure load from outside is high, the resistance to the pressure from outside is excellent and the assembling property into module (low leakage rate at the adhered part) is satisfactory at the same time. The present invention also provides a method for manufacturing the same, and a blood purification module.

Hollow fiber membrane, method for manufacturing the same, and blood purification module

The present invention provides a highly water permeable hollow fiber membrane type blood purifier for medical use, which is excellent in safety and module-assembling ease and which has a high water permeability suitable for use in therapy of chronic renal failure. The present invention relates to a highly water-permeable hollow fiber type blood purifier comprising hydrophobic polymer hollow fiber membranes each of which contains a hydrophilic polymer, characterized in that the amount of the hydrophilic polymer eluted from the hollow fiber membrane is 10 ppm or less; in that the ratio of the hydrophilic polymer in the outer surface of the hollow fiber membrane is 25 to 50 mass %; in that the burst pressure of the hollow fiber membrane is 0.5 MPa or higher; and in that the coefficient of water permeability of the blood purifier is 150 ml/m/hr./mmHg or higher.

Highly water-permeable blood purifier of hollow-fiber membrane type

Growing community of inventors

Ohtsu, Japan

Shinya Koyama