Ajinomoto Co., Ltd.

Shinya Goto

Osamu Kurahashi

Tsuyoshi Nakamatsu

Yoshio Kawahara

Yoshimi Kikuchi

Eiichiro Kimura

A microorganism is utilized to fermentatively produce useful substances such as amino acids by cultivating the microorganism in a medium to allow a fermentative product to be produced and accumulated in the medium, and collecting the fermentative product, wherein the microorganism to be used is modified by introduction of at least one of a gene coding for a heat shock protein and a gene coding for a &sgr; factor which specifically functions for the heat shock protein gene to enhance expression amount of the heat shock protein in cells, whereby the microorganism is allowed to have added resistance to stress which would otherwise restrain growth of the microorganism and/or production of the fermentative product.

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Kawasaki, Japan

Shinya Goto