Keiichi Fukuda

Other

Keio University

Dnavec Corporation

Heartseed Inc.

Fukuda, Keiichi

Shinsuke Yuasa

Mamoru Hasegawa

Hideyuki Okano

Keijiro Sugimura

Uichi Koshimizu

Tomofumi Tanaka

Takuya Shimazaki

Akira Kunitomi

Kenichiro Shimoji

Tomohisa Seki

Mie Hara

An object of the present invention is to provide an agent for improving quality of an iPS cell, a method for producing an iPS cell, an iPS cell produced by such a method for production, and a composition for producing an iPS cell. The method for producing an iPS cell according to the present invention comprises the step of introducing (a) a nuclear reprogramming substance and (b) an H1foo gene or a gene product thereof into a somatic cell. High-quality iPS cells can be produced in greater quantity by introducing not only a nuclear reprogramming substance but also an H1foo gene or a gene product thereof into a somatic cell.

Method for producing high-quality iPS cells

An object of the present invention is to provide methods for producing iPS cells with low invasivity and high efficiency. The iPS cells can be produced with high efficiency using a method comprising the steps of culturing mononuclear cells derived from peripheral blood for 3 to 14 days in the presence of anti-CD3 antibody, and subjecting the cultured mononuclear cells to dedifferentiation.

Method for producing induced pluripotent stem cells

The present invention relates to muscle repair promoters for local application that contain a colony-stimulating factor (CSF) as an active ingredient. The muscle repair promoters of the present invention exhibit their effect at low doses, particularly when they are administered intramuscularly.

Method for promoting muscle repair comprising administering G-CSF at the site of injury

A method for inducing differentiation of ES cells into cardiomyocytes, which comprises contacting the ES cells with an agonist for G-CSF receptor.

Method for inducing differentiation into cardiomyocytes using G-CSF

For a method of inducing differentiation of cardiomyocytes from stem cells, a method is provided to induce efficiently and selectively differentiation of cardiomyocytes by such a method in which the stem cells are cultured to induce differentiation into cardiomyocytes in the presence of a substance that inhibits BMP signaling.

Method of inducing the differentiation of stem cells into myocardial cells

Growing community of inventors

Tokyo, Japan

Shinsuke Yuasa