Daiichi Pharmaceutical Co., Ltd.

Shinobu Kagami

Makoto Yoshihama

Hidetoshi Takahashi

Yoshikazu Ikeda

Kiyoshi Isono

Ken-ichi Kimura

Kousaku Takahashi

Makoto Ubukata

Makoto Ubutaka

Antibiotics RK-1061s having a novel chemical structure and a method of production thereof. They have a structural formula represented by general formula(I) wherein A represents Ror RCH(OR)CH. Rrepresents 3-methylglutaric acid residue and Rrepresents a sulfate group or a hydrogen atom. The process comprises culturing a ray fungus belonging to the genusand isolating RK-1061s from the culture.sp. SN-1061Ms (FERM BP-5800) is capable of stably producing RK-1061 at a high productivity.

Antibiotics RK-1061 and process for preparing the same

Antibiotics RK-1061s having a novel chemical structure and a method of production thereof. They have a structural formula represented by general formula(I) wherein A represents R or R CH(OR )CH . R represents 3-methylglutaric acid residue and R represents a sulfate group or a hydrogen atom. The process comprises culturing a ray fungus belonging to the genus Streptomyces and isolating RK-1061s from the culture. Streptomyces sp. SN-1061Ms (FERM BP-5800) is capable of stably producing RK-1061 at a high productivity.

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Shimotsuga-gun, Japan

Shinobu Kagami