Teijin Pharma Limited

Shinnosuke Hosoda

Ryan D White

Jun Shibata

Hidekazu Watanabe

Sakae Sugiyama

Gen Unoki

Kosuke Sasaki

Kenichiro Takagi

Asahi Kawana

Akinobu Maruyama

Kyohei Horie

Kunio Minamizono

Takuya Yokosaka

Emi Yokoyama

Masaki Koshimizu

Wei Zhao

Kenta Kato

Toshiyuki Kaneko

Nagasree Chakka

Susumu Takeuchi

A compound, represented by the following formula or a medically acceptable salt thereof, having an effect of regulating the activity of an androgen receptor. In the formula, X represents S, O; Z represents (R)-A-(CRR)&#x2014;(CRR); A represents aryl, heteroaryl; Rrepresents alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl; Rrepresents hydrogen, halogen, alkyl, cycloalkyl, phenyl; R3 represents hydrogen, halogen, alkyl, cycloalkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkenyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl, acyl, cycloalkylcarbonyl, benzoyl, spiroalkyl, adamantyl, silyl, RRNCO&#x2014;; Rand Rrepresent hydrogen, halogen, alkyl, phenyl, and cycloalkyl. 

Aminoazole derivative

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Tokyo, Japan

Shinnosuke Hosoda