Sumitomo Chemical Company, Limited

Sumitomo Pharmaceuticals Company Limited

Shinichi Yokota

Hiroshi Noguchi

Hiroshi Ochi

Hiroshi Ohtsuka

Masazumi Terashima

Masuhiro Kato

Kenji Irie

Ikuko Uezumi

A human monoclonal antibody, which has prophylactic and therapeutic effect to infections diseases caused by Pseudomonas aeruginosa, and the epitope of which is located in the outer core moiety of LPS of the microorganism. A hybridoma producing the human monoclonal antibody, and processes for preparing the antibody and hybridoma are also provided.

Human monoclonal antibody and hybridoma producing the same

A human monoclonal antibody, which has prophylactic and therapeutic effect to infectious diseases caused by Pseudomonas aeruginosa of serotypes A and H classified under the Japanese Committee's Classification, and the epitope of which is located at the common structure in the O-antigen of Pseudomonas aeruginosa of serotypes A and H. A hybridoma producing said human monoclonal antibody, and processes for preparing said hybridoma and antibody are also provided.

Human monoclonal antibody, and its production and use

Growing community of inventors

Takarazuka, Japan

Shinichi Yokota