Ssp Co. Ltd

Shinichi Morimoto

Susumu Sato

Junji Okawa

Toshio Yokoyama

Hiromichi Eto

Haruyoshi Honda

Kinichi Mogi

Hiroshi Hasegawa

Noriaki Shioiri

Koichi Tachibana

Kazuo Yamazaki

Noriyuki Kawamoto

Norimitsu Umehara

Tadashi Mikami

Hiroyuki Naito

Shigeru Adegawa

Yoshihisa Sada

Disclosed herein are an imidazole derivative represented by the following general formula (1): ##STR1## wherein R.sup.1 is a hydrogen atom, or an alkyl, alkoxy or alkoxycarbonyl group, and R.sup.2, R.sup.3 and R.sup.4 are the same or different from one another and are independently a hydrogen or halogen atom, an alkyl, halogenoalkyl, hydroxyl or alkoxy group, or the like, or a salt thereof, and a medicine comprising such a compound. The compound specifically suppresses the production of particular cytokine and is hence useful as an active ingredient for immune function modulators and the like.

Imidazole derivative and medicine comprising the same as active

Substituted quinolone derivatives represented by the following formula: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted (hetero)aryl group, R.sup.2 represents H or an alkoxycarbonyl, substituted aminocarbonyl, cyano or like group, and R.sup.3 and R.sup.4 each independently represent H or a substituted alkyl, aryl, amino or like group, and salts thereof; pharmaceuticals containing the same. These derivatives and salts have excellent anti-ulcer activities.

Substituted quinolone derivatives and pharmaceuticals containing the same

Growing community of inventors

Sakura, Japan

Shinichi Morimoto