Kabushiki Kaisha Kyoto Daiichi Kagaku

Syntex (u.s.a.) Inc.

Kabushiki Kaisha Kyoto Kaiichi Kagaku

Shinichi Kishimoto

Hiroshi Yamamoto

Hiroshi Hyodo

Kenichi Iwase

Masahiro Yoshioka

Shigeki Yamada

Shoji Kawai

Yoshikazu Furutani

Naoki Yamada

Toshio Miki

Teiji Tanaka

Kazushige Inoue

An autonomous continuous analysis method and apparatus using Dip and Read type analytical implements. A series of operations of taking out analytical implements, dipping them in the sample solution, optical measurement, calculation, and disposal of the used sample solution are performed automatically. The dip stage, in particular, is automated by use of an analytical-implement automatic supply device and an analytical implement automatic handling device which, holding an analytical implement, dips it in the sample solution, and sets it ona reaction turntable. A number of analytical implements are put in a storage section comprising a bottom section provided with an analytical implement groove and at least one inside surface which is parallel with the groove, are taken out one by one by the relative movement of the groove and in normal and reverse direction and by stopping in a specified position after confirming by a detector that an implement has been caught in the groove.

Method and apparatus of automatic continuous analysis using analytical

A portable analyzer is disclosed. The analyzer comprises in combination a housing, an optical system comprising a light source, a detector, and one or more means for activating the optical system in generating a signal in response to a test element, means for manually moving the test element from a first position to a second position corresponding to a point of initiation of an operative condition of the optical system, means biasing the moving means toward said first position for controlling movement of the test element from the second position to the first position, means cooperative with said optical system, for processing the signal, and means, cooperative with the means for processing the signal, for displaying the processed signal.

Portable analyzer

The test solution in the measuring cell is regarded to be divided into a plurality of sections, and the quantity of scattered light from each section is continuously measured to give a plurality of independent series of signal. This measurement is carried out by scanning the measuring cell with a minute light flux periodically to obtain a plurality of measurements in a period. Out of the series of signals obtained, those containing abnormal scattered light signal are eliminated to determine accurate concentration and reaction process.

Method of measurement using scattered light

A blood coagulation time measuring method comprising irradiating a mixture of blood plasma and reagent with a beam of specified amount of light, detecting changes in the amount of light scattered by the mixture, converting the resulting scattered light output signals to digital form at specified time interval, feeding the digital data to a computer, computing the difference between each input value and the input value immediately adjacent thereto with respect to time and storing the results, and determining the time, prior to the time at which a maximum difference value is obtained, at which a computed difference value corresponding to 1/n of the maximum difference value is obtained. The time thus determined is the end point of the coagulation time. A system for practicing this method is also disclosed.

Method and system for measuring blood coagulation time

A method of analyzing a liquid sample by applying the sample to a composite test paper composed of a strip plastic transparent film and a reflectivity reference or compensation paper piece and a plurality of color reaction test paper pieces affixed to the strip, feeding the test paper to a spectral reflectivity measuring device a predetermined period of time after the application, and calculating the corrected reflectivities of each of the paper pieces from the measured amounts of reflected light at varying wavelengths to determine the concentration of the abnormal substance contained in the test sample, free of measuring errors due to the color if any of the sample, differences in the color developed and variations in the thickness of the color reaction test paper pieces and reflectivity reference or compensation paper piece. A system for practicing this method is also disclosed.

Method of analyzing liquid samples and system for continuously

A method and device for testing a liquid such as urine for obtaining at least qualitative, but also quantitative, if desired, information in connection with a substance which may be present in the liquid. A reference body and at least one test body are dipped into and removed from the liquid which is to be tested, a suitable means being connected with the bodies to facilitate the dipping thereof into and the removal thereof from the liquid. The test body is capable of giving a color indication in connection with the substance while the reference body has characteristics substantially identical with those of the test cody except that the reference body is incapable of giving a color indication in connection with the substance. Thus, after removal of the bodies from the liquid the reflectivities thereof may be compared so as to give at least a qualitative, but also a quantitative, if desired, indication of the substance in connection with the liquid which is tested.

Method and device for testing liquids

A test strip of the type which is dipped into a liquid such as urine for indicating by color information with respect to the liquid. The test strip has a transparent backing on one side of which is located a color-reaction paper with a fastening layer situated between the paper and the backing for fastening the paper to the backing. The fastening layer is opaque and non-reflecting with respect to light, so that while light can pass freely through the backing it will reflected by the color-reaction paper without passing through the backing. The test strip is moved perpendicularly across an optical axis along which light is directed with the light traveling first through the transparent backing and then being reflected by the color-reaction paper. Signals are generated from the light passing through the backing and the light reflected by the color-reaction paper, with the timing of the signal from the reflected light being controlled by the signal from the light which has passed through the transparent backing. The signal from the light which has traveled through the backing is utilized to initiate a time interval after which the signal from the reflected light is generated so as to assure that the operation of the structure providing the signal from the reflected light takes place when the color-reaction paper intersects the optical axis.

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Kuze, Japan

Shinichi Kishimoto