Nikon Corporation

The University of Tokyo

Topcon Corporation

Origin Electric Company, Limited

Shingo Ueno

Takanori Ichiki

Atsushi Saito

Hisao Osawa

Hirofumi Shiono

Kiyomi Watanabe

Ryousuke Ito

Ryo Kobayashi

Naoto Nemoto

Manish Biyani

Shinichi Omaki

An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Ophthalmologic apparatus and ophthalmologic system

There is provided a method of manufacturing a protein array or peptide array suitable for an efficient screening of a functional protein or functional peptide. The method of manufacturing a protein array or peptide array includes the steps of: (a) preparing a nucleic acid immobilized on a solid support and a cell-free synthesis system in a reactor, in which a reactor array includes the reactor having a specific aperture shape and a protein capture molecule or a peptide capture molecule provided on at least a portion of wall surface and bottom surface in the reactor; and (c) synthesizing a protein or peptide from the nucleic acid using the cell-free synthesis system and immobilizing the protein or peptide in the reactor.

Method of manufacturing protein array or peptide array, method of identifying functional protein or functional peptide, protein array or peptide array, and functional protein or functional peptide identification kit

The present invention relates to a nucleic acid linker for producing a complex of mRNA, and a protein or a peptide which is encoded by the mRNA, the linker comprising: a spacer portion at the 5'-terminal; a polynucleotide portion hybridizable with at least a part of a sequence of the mRNA; and an arm portion which has a connection portion for the protein or the peptide at the 3&#x2032;-terminal, in which the spacer portion, the polynucleotide portion, and the arm portion form a single strand, and in which the polynucleotide portion contains a photoreactive base derivative.

Nucleic acid linker

A protein-immobilizing solid phase is a protein-immobilizing solid phase comprising an mRNA-nucleic acid linker-protein complex, obtained by linking the mRNA and the protein encoded by that mRNA through the nucleic acid linker, immobilized on the solid phase, wherein the nucleic acid linker has a photocleavage site and a solid phase binding site.

Protein-immobilizing solid phase, polynucleotide-immobilizing solid phase, and nucleic acid recovery method

A series resonant converter of the present invention includes an inverter circuit having at least a pair of a first and second switching device connected between two input terminals, a transformer having a primary winding and a secondary winding connected to the inverter circuit, a first and second resonant capacitor connected to a secondary side of the transformer and connected in series to each other between two output terminals, a first and second unidirectional device connected in series to each other, and a resonant induction device that is operated along with the first and second resonant capacitor and resonates in series. The first and second unidirectional device are configured such that current does not flow from the first and second resonant capacitor to the input terminal by preventing electric charge of the first and second resonant capacitor from being discharged to a primary side of the transformer.

Series resonant converter having a circuit configuration that prevents leading current

A series resonant converter circuit that reduces power loss is provided that includes an inverter circuit having at least a pair of first and second switching elements that is connected between DC input terminals, a transformer connected to this inverter circuit, a resonant inductance means that are connected in series to a primary winding wire or a secondary winding wire of the transformer, a primary-side resonant capacitor that is connected in series to the resonant inductance means through the first or second switching element, first and second secondary-side resonant capacitors that are connected to each other in series between the DC input terminals, first and second unidirectional elements that are connected to each other in series between the DC output terminals, and a resonant inductance means that cooperates with resonant capacitance from the primary-side resonant capacitor and the first and second secondary-side resonant capacitors to resonate in series.

Growing community of inventors

Tokyo, Japan

Shingo Ueno