Sysmex Corporation

Eisai R&d Management Co., Ltd.

Shingo Fujiyama

Shigeki Iwanaga

Yoshihiko Norimine

Masaya Okada

Takafumi Motoki

Keiko Yoshikawa

Yuji Kazuta

Hiroyuki Amino

Yuma Oka

Masatoshi Suganuma

Kazuto Yamashita

Yoichi Nishikawa

Daiki Hara

Disclosed is: a fluorescent dye comprising a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy.

Fluorescent dye and use thereof

A cell information acquisition method may include: binding a binding substance to a receptor on a cell membrane surface of a cell, the binding substance being bindable to the receptor; permeabilizing a cell membrane of the cell after the binding; labeling a receptor in an intracellular area of the cell with a binding substance labeled with a first labeling substance after the permeabilizing; causing a specimen including the cell to flow through a flow path after the labeling; irradiating the cell included in the specimen flowing through the flow path with light; and acquiring a signal based on light generated from the first labeling substance in the cell irradiated with light.

Cell information acquisition method and cell information acquisition device

Growing community of inventors

Kobe, Japan

Shingo Fujiyama