Other

Kabushiki Kaisha Topcon

Nidek Co., Ltd.

Seventh Dimension Design, Inc.

Shin Yoneya

Masayuki Takasu

Gholam A Peyman

Tsuguo Nanjo

Yutaka Yoneda

Motoyoshi Baba

Hiroto Kuroda

A method for diagnosing the probability of the onset of glaucoma or the degree of the advancement of glaucoma by observing connective tissue of lamina cribrosa and its neighboring part of retina, namely the movable nature of lamina cribrosa in relation to retina.

Method for diagnosing glaucoma by observing connective tissue of lamina cribrosa

Provided is an observation device and a method of observing capable of clearly obtaining information relating to a boundary part where a medium inside an observation object changes. An observation device () is a device for observing an observation object () including a sensitivity factor in which a dipole moment changes by sensing an electromagnetic wave (). An output part () outputs the electromagnetic wave () and the dipole moment of the sensitivity factor included in the observation object () is changed by the electromagnetic wave (). A detector part () detects, of the electromagnetic wave () outputted from the output part (), a signal electromagnetic wave () which comes through the observation object () and a reference electromagnetic wave () which bypasses the observation object (). A control part () analyzes the structure of the observation object () based on the detection results of the detection part (). The electromagnetic wave () is pulse laser light which is intermittently outputted in pulse waveform. The wavelength of the electromagnetic wave () is arranged within the wavelength absorption band of the sensitivity factor.

Observation device and method of observing

In one aspect, the invention features a method and device for measuring blood concentration of a substance such as glucose in the aqueous humor by illuminating the aqueous humor with a light source at a frequency that is absorbed by the substance to the measured, and then sensing photoacoustically generated sound waves originated within the aqueous humor as a consequence of illumination by the light source. The blood concentration can be estimated from the amplitude of the sound waves received. The method may be combined with other optical techniques for glucose measurement and/or with optical or ultrasonic techniques for topographic mapping of eye structures.

Photoacoustic measurement of analyte concentration in the eye

The present invention relates to a method, including the steps of mapping at least a portion of the fundus of the eye by forming a plurality of pixels, estimating the oxygen saturation level at each of the plurality of pixels, superimposing the fundus maps on maps of anatomic borderlines, and comparing portions of the superimposed fundus maps to predetermined fundus maps.

Method of detecting glaucoma

A fundus photographing device for conducting infrared fluorescence photography on a fundus of an examinee's eye after intravenously injecting a fluorescent agent which emits fluorescence of an infrared region into veins is disclosed. This device includes an illumination optical system for illuminating the fundus with exciting light, thereby exciting the injected fluorescent agent, the exciting light being of wavelengths in a wavelength region of not maximum absorption but maximum fluorescent intensity of the fluorescent agent.

Fundus photographing device

An apparatus for clogging blood vessels of an eye fundus includes an illuminating optical system (1) for illuminating an eye fundus of a subject, who has been given an injection of an infrared fluorescent agent, with infrared rays of light and exciting the infrared fluorescent agent so as to generate infrared fluorescence, a photographic optical system (2) for observing and photographing the eye fundus, and a projecting optical system (21) for projecting a laser beam of light having a specific wavelength onto the subject who has been also given an injection of a photosensitive substance which undergoes a photochemical change by the laser beam. In the apparatus, while a region which emits infrared fluorescence is being observed, the laser beam is projected onto the photosensitive substance so as to clog blood vessels of a diseased part in the depth of the eye fundus.

Medicine for clogging blood vessels of eye fundus

The present invention relates to a fundus camera for photographing vascular condition of the retina in medical examination for checking health, and it comprises a retina illuminating system for projecting infrared illuminating light beam to the retina to be examined, a first barrier filter having a first transmission wavelength range and a second barrier filter having a second transmission wavelength range shifted toward longer wavelength range, said two barrier filters being interchangeable with each other, and a photographing system for angiography of the retina to be examined through either the first or the second barrier filters, whereby a proper fluorescent vascular image is photographed even when fluorescent light wavelength from the retina is changed with the lapse of time.

Growing community of inventors

Maebashi, Japan

Shin Yoneya