Crinetics Pharmaceuticals, Inc.

Shimiao Wang

Jian Zhao

Yunfei Zhu

Sangdon Han

Sun Hee Kim

Mi Chen

Joseph Pontillo

Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.

Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof

Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Somatostatin modulators and uses thereof

Nonpeptide somatostatin type 5 receptor agonists and uses thereof

Described herein are compounds of Formula (I), or a pharmaceutically acceptable salt, solvate, diastereomeric mixture, or individual enantiomers thereof, that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity. 

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San Diego, CA, United States of America

Shimiao Wang