Chinese Academy of Medical Sciences

Beijing Jiuyu Oncolgy Co., Ltd.

Bening Zhen Huikang Biological Tech. Co., Ltd.

Shihong Liu

Zhiqiang Liu

Zengqiang Yuan

Xiaowen Xing

Bingshui Xiu

Wei He

Yulin Cao

Cui Wang

Juntang Lin

Xiayun Li

Chengqian Lu

An application of hyaluronic acid in preparing medicines for preventing or treating ferroptosis-related diseases is provided, and an application of hyaluronic acid or salts of hyaluronic acid or derivatives of hyaluronic acid in preparing medicines for inhibiting ferroptosis is also provided. According to the present application, the anti-ferroptosis function of hyaluronic acid is disclosed. The hyaluronic acid is the first natural extracellular matrix material with anti-ferroptosis function found at present. The hyaluronic acid is one of the components of natural extracellular matrix and exists in large quantities in human body and is also a widely used material in clinic.

Application of hyaluronic acid in preparing medicines for preventing or treating ferroptosis-related diseases

A fusion imaging gene and lentiviral expression plasmid, lentivirus and cell, and preparation methods and applications thereof are provided. The fusion imaging gene includes bioluminescence imaging gene, fluorescent protein gene and calcium imaging gene. The three genes are linked by linkers. The fusion gene is inserted into a modified lentiviral expression plasmid to obtain lentivirus particles carrying the fusion imaging gene.

Fusion imaging gene and lentiviral expression plasmid, lentivirus, cell, preparation methods and applications thereof

The infusion pump for stem cells includes a liquor storage device and an infusion pipe. The inner wall of the liquor storage sac of the liquor storage device and inner walls of the infusion pipe are provided with an anionic protective film to prevent stem cells from adhering to the infusion pump by mutual repulsion between anions. The infusion method includes checking an infusion pump for integrity, losing a liquor stop clamp, injecting a mixed liquor of stem cells and medicine, covering a protective cap, opening the liquor stop clamp, closing the liquor stop clamp for use, connecting an external cone joint with a venous cannula, and then opening the liquor stop clamp. The method also includes steadily placing the liquor storage sac on a horizontal plane using an auxiliary placing device, and after infusion ends, closing the liquor stop clamp, and disconnecting the external cone joint.

Infusion pump and infusion method dedicated for stem cell

Growing community of inventors

Beijing, China

Shihong Liu