Bgi Shenzhen

Sun Yat-sen University Cancer Center (sysucc)

Shihong Chen

Yun Wang

Yue Shen

Xun Xu

Huanming Yang

Tai Chen

Weijian Mei

Jiehai Yu

Shuoyu Xu

Longying Liu

Le'en Liao

Muxu Zheng

Wu Jiang

Kang Kang

Wanjun Yang

Zhigang Hong

Peirong Ding

A system for predicting immunotherapeutic efficacy for colorectal cancer performs operations of: obtaining a digital image of a biological tissue a colorectal cancer patient; predicting a tissue type parameter and a cell type parameter corresponding to the digital image of the biological tissue based on a classifier algorithm model; determining a plurality of cell feature parameters corresponding to the digital image of the biological tissue based on a calculating rule of a plurality of cell features corresponding to the tissue type parameter and the cell type parameter; calculating a therapeutic efficacy score corresponding to the colorectal cancer patient according to the plurality of cell feature parameters and a predetermined parameter scoring rule; and the therapeutic efficacy score is configured to predict the therapeutic efficacy of the colorectal cancer patient receiving immunotherapy.

System for predicting immunotherapeutic efficacy for colorectal cancer

A method for encoding and storing text information using DNA as a storage medium, a decoding method therefor and an application thereof. The method for using DNA to store text information comprises: encoding characters into computer binary digits by means of encoding, and converting the binary digits into DNA sequences by means of transcoding; and artificially synthesizing the DNA sequences encoded with character information, positioning the characters by means of a designed ligation adapter, and assembling the DNA sequences encoded with the character information according to a pre-set order. The method for using DNA to store text information has the advantages of a small storage volume, a large storage capacity, a strong stability and low maintenance costs.

Method for using DNA to store text information, decoding method therefor and application thereof

Disclosed is a high-throughput detection method for a DNA synthesis product. According to the method of the present invention, a high-throughput sequencing technology is applied to detection of a DNA chip synthesis product through a mixed library construction strategy, so that costs of product detection and accurate product screening are reduced.

High-throughput detection method for DNA synthesis product

Growing community of inventors

Guangdong, China

Shihong Chen