Institute of Occupational Safety and Health Council of Labor Affairs

Academia Sinica

National Taiwan University

Wellhead Biological Technology Corp.

Institute of Occupational Safety & Health, Council of Labor Afffairs,

National Defense Medical Center & Academia Sinica

Shih-Hsiung Wu

Chung-Yun Gau

Chung-Yi Wu

Ann Chen

Shuk-Man Ka

Chi-Fu Tai

Cheng-Yang Hsu

Chen-Chung Lin

Ke-Feng Lin

Kuo-Feng Hua

Sheau-Long Lee

Yu-Chieh Lee

Jin-Town Wang

Yulin Lam

Feng-Ling Yang

Choung-Fai Wang

Hwa-Teng Lee

Shuo-Jen Lee

Huoy-Shyi Tsay

Yeh-Liang Hsu

I-Ming Lee

Meng-Chiao Ho

Wan-Ling Wu

The present invention provides a lectin fromoras diagnostic reagents for IgA nephropathy. The present invention also provides a diagnostic kit for detecting Galactose-deficient IgA1 (Gd-IgA1), comprising RussiaSea-001 (also called as CGL) isolated fromor RussiaSea-002 (also called as MTL) isolated from. The present invention further provides a method for detecting Gd-IgA1 using RussiaSea-001 or RussiaSea-002.

Diagnostic kits and methods configured to rapidly and non-invasively determine physiologic levels of galactose-deficient IgA1 (Gd-IgA1) in the subject of IgA nephropathy

Disclosed herein is a glycoconjugate vaccine conferring protection against a Gram negative pathogen infection, a method of manufacturing the glycoconjugate vaccine, and use of the glycoconjugate vaccine for treating bacterial infection. The glycoconjugate vaccine of the present disclosure has the structure of formula (I), wherein, L is a maleimide-type linker, which is connected to the carrier protein via a maleimide bond formed therebetween; and n and m are independently an integral or a non-integral number between 2 and 20.

Glycoconjugate vaccines, preparation method and uses thereof

The disclosure provides various immunogens comprising a repeat unit of saccharide ofCPS, which has a formula selected from the group consisting of Formulae (I) to (VI) as described herein. Also provided are vaccines including one or more immunogens selected from Formula (I) to (VI) and methods of eliciting an immune response against aand preventing infection ofby using an immunogen of the invention.

capsule polysaccharide vaccines

The preset invention relates to a method for treating inflammation comprising administering a subject in need thereof with a therapeutically effective amount of polyenylpyrrole derivatives of formula (I) or a pharmaceutically acceptable salt thereof.

Use of polyenylpyrrole derivatives for treating inflammation

A fusion gene encodingWR-220 keratinase is disclosed. The fusion comprises: (a) a first DNA sequence encoding a protein secretion signal peptide, located at the N-terminus of the fusion gene; (b) a second DNA sequence encoding an inhibitory domain ofWR-220 keratinase, linked in translation frame with the first DNA sequence; and (c) a third DNA sequence encoding a catalytic domain ofWR-220 keratinase, linked in translation frame with the second DNA sequence, wherein the fusion gene is a non-naturally occurring chimeric DNA. Also disclosed are a method for preparation of the catalytic domain ofWR-220 keratinase, and use of theWR-220 keratinase.

Heat stable keratinase and use thereof

A trench shield includes a pair of shielding panels for protecting opposite side walls of a trench excavation, two side frames are provided for restively adjustably securing the two shielding panels on the two side frames, and have a plurality of brace members spaced between the two side frames for retaining the two side frames and the two shielding panels, and two rolling devices respectively are mounted on a front bottom portion and a rear bottom portion of the trench shield for carrying the trench shield to be ridable and movable on a pipe under construction in the trench excavation. Upon rolling of the rolling devices on the constructing pipe, the trench shield will be conveniently moved on the pipe without any obstruction.

Trench shield directly ridable and movable on a constructing pipe

A trench shield includes: a pair of shielding wheels rotatably mounted on a pair of retaining plates; a plurality of brace members passing through two retaining plates for retaining the two shielding wheels, each shielding wheel formed as a protective circular panel for shielding a side wall of a trench excavation for preventing collapse of the trench walls; and two control devices each provided for locking or unlocking each shielding wheel on each retaining plate; whereby upon unlocking of the wheels from the retaining plates and upon rolling of the wheels in the trench, the trench shield will be forwardly moved conveniently and smoothly.

Trench shield having wheels simultaneously provided for protection and

A locomotion platform is composed of a platform main body, a waist holding device, a signal fetching circuit, and a monitoring system. The platform main body consists of a platform structure body, a perforated platform face plate, position sensors, and balls located over the position sensors. The waist holding device consists of a waist ring for catching the waist of a user, and a fastening member for fastening the waist holding device with the platform structure body. The signal fetching circuit is intended to fetch the signals generated by the position sensors. The monitoring system is intended to receive the output signals of the signal fetching circuit and is provided with a software for computing the displacement generated by the strolling of the user on the platform main body. The results of computation are exhibited on a monitor.

Locomotion platform

An advance warning device for monitoring the working conditions of a hydraulic braking system of a motor vehicle is composed of a plurality of sensors and a controller in communication with the sensors for processing the signals transmitted by the sensors so as to provide the operator of the motor vehicle with an advance warning signal as to likelihood of the brake failure. The sensors are intended to monitor respectively the temperature of the brake lining piece, the temperature of the brake fluid kept in the distribution pump, the water content of the brake fluid of the hydraulic braking system, and the hydraulic pressure of the hydraulic braking system.

Advanced warning device for monitoring the working conditions of

An industrial safety helmet comprises a shell of a semioval shape, a crad and a chin strap. The shell has one or more flexures capable of strengthening the shell and of promoting air circulation of the shell. The flexures are provided respectively at the front end thereof with an air inlet while at least one of the flexures is provided at the rear end thereof with an air outlet. The cradle has an energy-absorbing mechanism. The chin strap is provided with a detachable adhesive buckling mechanism.

Growing community of inventors

Taipei, Taiwan

Shih-Hsiung Wu