Utah State University

Shiguang Yang

Mark C Healey

John R Forney

Jon Y Takemoto

Karl A Werbovetz

A method for controlling infections caused by protozoans, such as,and,The method comprises using syringomycin-family lipodepsipeptides, preferably syringomycins such as syringomycin E, to control or prevent infections caused by protozoans. The method is directed to therapeutic treatment of mammals, such as humans, exposed to protozoans, and additionally as a prophylactic treatment in immunocompromised subjects at high risk for contracting protozoan infections.

Method of controlling protozoan infections using syringomycin-family lipodepsipeptides

A method for controlling infections caused by Cryptosporidium parvum. The method comprises using protease inhibiting compounds, preferably serine protease inhibitors, to inhibit excystation, invasion, and parasite maturation and development. The method is directed to therapeutic treatment of mammals, such as humans, exposed to C. parvum, and additionally as a prophylactic treatment in immunocompromised subjects at high risk for contracting cryptosporidiosis.

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Logan, UT, United States of America

Shiguang Yang