Asahi Kasei Pharma Corporation

Meiji Co., Ltd.

Tokyo University of Marine Science and Technology

Ichibiki Co., Ltd.

National University Corporation Tokyo University of Marine Science and Technology

Shigeyuki Imamura

Takuji Kouzuma

Junichi Sumitani

Issei Yoshioka

Motoo Arai

Toshihiko Kumazawa

Junichi Kawashima

Atsuhisa Nishimura

Shinichi Sakasegawa

Kazunaga Yazawa

Yasuhito Tashiro

Yoshiaki Ikura

Tomoyuki Susa

Yoko Nagai

Shoji Gotoh

The present invention provides a method for producing a composition containing 2-acyl-lysophosphatidylserine, including (a) a step of obtaining a composition containing phosphatidylserine by allowing phospholipase D to act on a raw material containing phosphatidylcholine in the presence of serine and (b) a step of obtaining a composition containing 2-acyl-lysophosphatidylserine by allowing phospholipase A1 to act on the composition containing phosphatidylserine in the presence of one or more additives selected from the group consisting of the following (I), (II), and (III), in which (I) one or more salts selected from the group consisting of sulfate salts, phosphate salts, nitrate salts, citrate salts, and tartarate salts of monovalent cations, (II) a gum, and (III) an emulsifier.

Composition containing 2-acyl-lysophosphatidylserine and method for producing the same

Composition for accurately assaying a glycated protein by: 1) avoiding effects of globulin and ascorbic acid components, 2) siabilizing proteases and at least enzymes acting on glycated amino acids; 3) accurately assaying albumin; and 4) assaying glycated albumin while avoiding the effects of glycated hemoglobin, and an assay method are provided. Thus, the contents of a glycated protein and glycated albumin can be more accurately determined.

Composition for assaying glycated proteins

Provided is a novel and useful method of measuring pyrophosphate in a sample. There may be provided a novel and useful method of measuring pyrophosphate in a sample using pyruvate orthophosphate dikinase, nicotinamide-nucleotide adenylyltransferase, and dehydrogenase.

Method of measuring pyrophosphate

Stabilizers for colorants used for detection of enzymatic reactions, having a cyclodextrin and a catalase; reagents including stabilizers; and methods of use of such stabilizers and reagents.

Reagent containing protease reaction promoter and/or colorant stabilizer

Diglyceride solutions for lipase activity determination, comprising at least one diglyceride, a low concentration buffer, and a nonionic surfactant.

Diglyceride solutions for lipase activity determination

Compositions for accurately assaying a glycated protein by: 1) avoiding effects of globulin and ascorbic acid components, 2) siabilizing proteases and at least enzymes acting on glycated amino acids; 3) accurately assaying albumin; and 4) assaying glycated albumin while avoiding the effects of glycated hemoglobin, and an assay method are provided. Thus, the contents of a glycated protein and glycated albumin can be more accurately determined.

Composition for assaying glycoprotein

Growing community of inventors

Izunokuni, Japan

Shigeyuki Imamura