Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo

Shigeyuki Arai

Masashi Kurimoto

Yasushi Nishizaki

Shigeharu Fukuda

Hajime Aga

Toshio Kunikata

Tetsuo Kimoto

Chiyo Yoshizane

A physiologically active extract comprising an ethyl acetate-soluble ingredient of an indigo plant, which is obtainable by soaking a raw indigo plant in an organic solvent used for extraction. The ethyl acetate-soluble ingredient includes tryptanthrin, 3,5,4&prime;-trihydroxy-6,7-methylenedioxy-flavone, kaempferol, 3,5,7,4&prime;-tetrahydroxy-6-methoxy-flavone, gallic acid, caffeic acid, indirubin, pheophorbide a, and methylpheophorbide a.

Physiologically active extract obtained from indigo plant polygonum tinctorium

An orally or parenterally administrable agent for anti-osteoporosis, comprising trehalose as an effective ingredient and optionally another ingredients, that exerts a satisfactory therapeutic/prophylactic effect on osteoporosis with lesser side effects.

Agent for anti-osteoporosis

An antitumor agent comprising as an effective ingredient 3-�4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl!-2-propenoic acid obtained from propolis and/or its physiologically acceptable salt(s). The agent exerts a strong antitumor activity without substantially inducing side effects.

Antitumor agent

Growing community of inventors

Okayama, Japan

Shigeyuki Arai