Ube Industries, Inc.

Astra Zeneca U.k. Limited

Other

Sankyo Company, Limited

Nissan Chemical Industries Limited

Nippon Chemiphar Co., Ltd.

Shigeyoshi Nishino

Hidetaka Shima

Kenji Hirotsu

Katsumasa Harada

Takashi Harada

Hiroyuki Oda

Shinobu Suzuki

Kiyotaka Yoshii

Shuji Yokoyama

Keiji Iwamoto

Yoji Omata

Tomio Kimura

Hiroyuki Koike

Teruhiko Inoue

Fumitoshi Asai

Akira Nakamura

Atsuhiro Sugidachi

Yasunori Tsuzaki

Tetsuro Shimano

Takeshi Takahashi

Naoko Okada

Shoji Shikita

Kunio Kobayashi

Masashi Shirai

Paul Michael Murray

Minoru Nishimura

Masao Yamamoto

Hiroshi Sasaki

Takafumi Iwasa

Kazuaki Kakita

Yoshihisa Kakuta

Toshio Furuya

Kimihiko Yoshimura

Naoako Okada

Shinya Takigawa

Luis-Manuel Vaz

Debra Ainge

An aryloyl(oxy or amino)pentafluorosulfanylbenzene compound having pharmacological action. The aryloyl(oxy or amino)pentafluorosulfanylbenzene compound is represented by general formula (A-I), a pharmaceutically acceptable salt thereof, and a prodrug thereof, wherein all of parameters represent the same meanings as defined in the specification.

Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof

The present invention relates to a binuclear ruthenium complex dye having a higher absorption coefficient and capable of absorbing light of longer wavelength for realizing a photoelectric conversion element and a photochemical cell which may convert solar light into electricity over a wide wavelength range and exhibit high photoelectric conversion efficiency; and a binuclear ruthenium complex dye for realizing a photoelectric conversion element and a photochemical cell which may have high durability.

Photoelectric conversion element comprising binuclear ruthenium complex dye having a substituted bipyridyl group, and photochemical cell

A process for producing a quinazolin-4-one compound having the formula: [wherein R, R, Rand Reach represents a group not participating in the below-mentioned reaction, and R, R, Rand Rcan be combined together to form a ring] which comprises reacting an anthranilic acid derivative having the formula: [wherein Ris a hydrogen atom or a hydrocarbyl group] with a formic acid derivative in the presence of an ammonium carboxylate.

Process for producing quinazolin-4-one derivative

A 4-aminoquinazoline derivative can be obtained by the steps of reacting quinazolin-4-one or its derivative with a chlorinating agent in a first organic solvent in the presence of an organic base, and subsequently reacting the reaction product with an amine compound represented by the formula R&#x2014;NH&#x2014;R(each of Rand Rrepresents hydrogen or an optionally substituted hydrocarbyl group) in the presence of a second organic solvent.

Process for producing 4-aminoquinazoline compound

6,7-Bis(2-methoxyethoxy)quinazolin-4-one of formula (5) useful in synthesis of an anti-cancer drug can be prepared by a reaction of ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate of formula (4) with an orthoformic acid in the presence of an ammonium acetate: 

Process for preparation of 6, 7-bis(2-methoxyethoxy) quinazolin-4-one

A polycyclic pentafluorosulfanylbenzene compound represented by the following general formula (1) and a process for producing the polycyclic pentafluorosulfanylbenzene compound which comprises reacting a specific pentafluorosulfanylbenzene compound with a specific boronic acid compound are provided. The polycyclic pentafluorosulfanylbenzene compound is a novel compound and can be produced by the process industrially advantageously. (Rto Reach independently represent hydrogen atom or fluorine atom, Rrepresents a hydrocarbon group having at least two cyclic structures which may have substituents, and Z represents keto group, thioketo group, methylene group or difluoromethylene group.)

Polycyclic pentafluorosulfanylbenzene compound and process for producing the compound

An object of the present invention is to provide an industrially suitable process for preparing an imidazolidin-2,4-dione compound which is safe, simple and easy to prepare the imidazolidin-2,4-dione compound with high yield, which is a useful compound, for example, as a material for decomposing a harmful halogenated aromatic hydrocarbon compound such as dioxin, etc., an electroless silver plating solution for electronic parts, or a diazo copying material, etc. This object can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises subjecting a 4,5-dihydroxy-2-imidazolidinone compound, (1) to dehydration reaction in the presence of an acid catalyst(s); or (2) to reaction at 100 to 300&#xb0; C. Or, it can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises reacting a mixed solution of a urea compound, glyoxal, and a base at 20 to 300&#xb0; C. Also, an object of the present invention is to provide a method for acquiring a 4,5-dihydroxy-2-imidazolidinone from an aqueous solution containing a 4,5-dihydroxy-2-imidazolidinone by a simple and easy method. This object can be solved by a process for acquiring a solid state 4,5-dihydroxy-2-imidazolidinone compound which comprises mixing an organic solvent with an aqueous solution containing a 4,5-dihydroxy-2-imidazolidinone compound, and subjecting the mixture to azeotropic distillation.

Process for preparing imidazolidin-2,4-dione compound and method for acquiring solid state 4,5-dihydroxy-2-imidazolidinone compound

Disclosed is a commercially suitable method for producing a 1-substituted-5-acylimidazole compound. A 1-substituted-5-acylimidazole compound is produced with a high position selectivity by reacting an N-substituted amidine compound or a salt thereof with a ketone compound in the presence of a base.

Method for producing 1-substituted-5-acylimidazole compound

The present invention relates to a process for preparing tetrahydropyran-4-one represented by the formula (1): which comprises reacting at least one kind of dihydropyran-4-one and pyran-4-one represented by the formula (2): 

Processes for preparing tetrahydropyran-4-one and pyran-4-one

The present invention is to provide a process for preparing an alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound represented by the formula (1):   

Processes for preparing alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound and 4-acyltetrahydropyrane

A dibenzothiazepine compound is suitably prepared by subjecting a 2-amino-2'-carboxy-diphenylsulfide compound to dehydration-condensation reaction in the presence of an acidic catalyst; the 2-amino-2&#x2032;-carboxy-diphenylsulfide compound is suitably prepared by reducing a 2-nitro-2&#x2032;-carboxy-diphenylsulfide compound in a lower aliphatic ester solvent; and the 2-nitro-2&#x2032;-carboxy-diphenylsulfide compound is suitably prepared by reacting a nitrobenzene compound with a thiosalicylic acid compound in a mixture of a lower aliphatic alcohol and water.

Process for preparing dibenzothiazepine compounds

The present invention is to provide a process for preparing a 4-aminopyrimidine compound represented by the formula (3): 

Process for preparing 4-aminopyrimidine compound

The present invention relates to a process for preparing 4-aminotetrahydropyran compound and an acid salt thereof represented by the formula (1):  

Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same

The present invention provides a process for preparing an N,N'-dialkoxy-N,N&#x2032;-dialkyl oxamide represented by the formula (3):  

Process for preparing N,N'-dialkoxy-N, N&#x2032;-dialkyl oxamide

A 5-fluorooxindole-3-carboxylic acid ester represented by a formula (2): 

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Ube, Japan

Shigeyoshi Nishino