Osaka University

Shigeru Sugiyama

Tsuyoshi Inoue

Hiroaki Adachi

Kazufumi Takano

Hiroyoshi Matsumura

Yusuke Mori

Norihiko Nishizawa

Kazuyoshi Itoh

Mihoko Hirao

Hiroshi Yoshikawa

Satoshi Nakayama

Yoshinori Takahashi

Satoshi Murakami

Yuusuke Mori

Ryota Murai

Shutaro Ishida

Masateru Kurata

Murakami Satoshi

The present invention provides a target substance transfer method, a crystal production method, a composition production method, and a target substance transfer device, which allow the concentration of a target substance to be increased easily and effectively. The target substance transfer method is a method for transferring a target substancefrom a first phasethat is a liquid or solid phase containing the target substanceto a second phaseincluding: a phase approximation step of bringing the first phaseand the second phaseinto close proximity; and a bubble collapse step of forming bubbles in the vicinity of a boundary between the first phaseand the second phaseand then causing the bubbles to collapse.

Target substance transfer method, crystal production method, composition production method, and target substance transfer device

Provided are a method for observing protein crystal, wherein the growth process of the protein crystals is nondestructively and three-dimensionally monitored on a real-time basis and the growth of the crystals is controlled at a high accuracy to thereby enable the formation of single crystals having good qualities, which comprises observing the protein crystals, said protein crystals having been produced by a crystallization method using a gel, by an OCT measurement using light emitted from an ultrawideband light source; a method for observing protein crystals wherein the ultrawideband light source is an ultrawideband supercontinuum light source; a method for observing protein crystals wherein the center wavelength of the light emitted from the ultrawideband supercontinuum light source is a 0.8 &#x3bc;m band; and a method for observing protein crystals wherein the monitoring of the protein crystals is a monitoring by an in situ measurement.

Method for observing protein crystal

Growing community of inventors

Suita, Japan

Shigeru Sugiyama