Ube Industries, Inc.

The Japanese Red Cross Society

Showa Denko K.k.

Shigeru Sasakawa

Masayuki Shiba

Naotaka Hamasaki

There is disclosed an additive solution for blood preservation and activation, which comprises a phosphoenolpyruvic acid represented by the following formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, R.sub.2 and R.sub.3 represent a hydrogen atom, an alkali metal or an alkyl group having 1 to 12 carbon atoms, respectively, an L-ascorbic acid-phosphate or its pharmaceutically acceptable salt, a saccharide, adenine and a pharmaceutically acceptable organic buffer.

Additive solution for blood preservation and activation

There is disclosed an additive solution for blood preservation and activation, which comprises a phosphoenolpyruvic acid represented by the following formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, R.sub.2 and R.sub.3 represent a hydrogen atom, an alkali metal or an alkyl group having 1 to 12 carbon atoms respectively, a saccharide, adenine and an organic acid and/or a pharmaceutically acceptable alkali metal salt of the organic acid.

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Tokyo, Japan

Shigeru Sasakawa