Rohto Pharmaceutical Co., Ltd.

Daiichi Pharmaceutical Co., Ltd.

Shigeru Kametaka

Shin'ichi Hayashi

Katsuhiko Morisaki

Kiyotsugu Higashi

Akiyoshi Yoshida

Reiko Izumi

Tetsuo Koike

Akira Handa

Kinya Kameda

Shinichi Hayashi

Tadaaki Miyazaki

A pharmaceutical composition for treating periodontal diseases which comprises one or more of therapeutically active ingredients admixed with a polymer capable of dissolving in an aqueous medium of pH 4.0 or higher.

Pharmaceutical composition for periodontal diseases

A method for treating or preventing periodontal disease which comprises administering ofloxacin or salts thereof locally to periodontal tissue are disclosed. The method is excellent on the treatment of periodontal disease in small dose without disturbance of bacterial flora.

Method for treating or preventing locally periodontal disease

A pharmaceutical composition for treating periodontal diseases which comprises one or more of therapeutically active ingredients dispersed in a carrier, characterized in that said carrier consists of

Pharmaceutical composition for treating periodontal

A pharmaceutical composition useful for treatment of periodontal diseases which comprises one or more active ingredients effective for the treatment of periodontal diseases, characterized in that said active ingredient or ingredients are dispersed in collagen.

Pharmaceutical composition for the treatment of periodontal disease

A pharmaceutical composition for the prevention of dental caries which comprises as essential component(s) one or more of pentacyclic acid triterpenes of the formula: ##STR1## wherein R.sub.1 represents CH.sub.3, CHO or CH.sub.2 OH, R.sub.2 and R.sub.3 independently represent CH.sub.3 or COOH, R.sub.4 represents H, CH.sub.3, COOH or COOCH.sub.3, R.sub.5 and R.sub.6 independently represent H, CH.sub.3 or OH, and A represents two Hs or O, and their salts.

Pharmaceutical composition for the prevention of dental caries

A method of enhancing a fungus-lytic activity of .beta.-1,3-D-glucanase which comprises using said glucanase in the presence of one or more of the activators selected from the group consisting of sodium lauroylsarcosinate, polyoxyethylene alkylphenyl ether, polyoxyethylene alkyl ether, polyoxyethylene polyoxypropylenealkyl ether, benzalkonium chloride, ammonium chloride, chlorhexidine glucuronate, methylparaben, propylparaben, trypsin, Pronase.RTM. and Alcalase.RTM.. A method of enhancing a fungus-lytic activity of .beta.-1,3-D-glucanase which comprises using two .beta.-1,3-D-glucanases of different origins is also provided.

Method for enhancing a fungus-lytic activity of .beta.-1,3-D-glucanase

A cleaning composition for an artificial denture which comprises .beta.-1,3-glucanase as an essential component together with one or more of suitable carriers.

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Kashiwara, Japan

Shigeru Kametaka