Ishihara Sangyo Kaisha, Ltd.

Shigeo Murai

Takahiro Haga

Nobuyuki Sakashita

Yuji Nakamura

Shooichi Honzawa

Ryuzo Nishiyama

Yasuhiro Tsujii

Fumio Kanamori

Tsunezo Yoshida

Kazuyuki Maeda

Akihiko Isogai

Toshio Nakajima

Hiroshi Yoshizawa

Fumio Kimura

Tadaaki Toki

Hiroshi Kikugawa

Takao Awazu

Tadashi Nakamura

Takeshi Ohshima

Tatsuo Isogai

Takayoshi Ando

Norio Adachi

Hiroshi Sasaki

Hisayoshi Jonishi

Tohru Koyanagi

Toshihiro Tanaka

Katsuyoshi Murakami

Kanichi Fujikawa

Yasuo Morishima

Tokiya Kimura

Makiko Sano

Chimoto Honda

Yoshiyuki Aoyama

Hitoshi Nakayama

Hisayoshi Jyonishi

Makiko Mitani

Soichiro Nagayama

Ryoji Koto

To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture. 

Method for producing pyrimidine compound

Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.

Process for producing toluidine compound

Pyrazole compounds, processes for their production and herbicides

A pyridonesulfonylurea compound of the formula (I) or its salt: ##STR1## wherein Q is ##STR2## for use as a herbicide, wherein the variables are hereinbelow defined.

Pyridonesulfonylurea compounds, process for their production and

A substituted pyridinesulfonamide compound or its salt represented by the following general formula (I): ##STR1## wherein A is CH or N; when A is CH, R.sub.1 and R.sub.2 may be either each independently a member selected from the group consisting of unsubstituted or substituted alkyl groups, unsubstituted or substituted alkenyl groups, unsubstituted or substituted cycloalkyl groups, and unsubstituted or substituted phenyl groups; when A is N, R.sub.1 is an unsubstituted or substituted alkyl group, R.sub.2 is an unsubstituted or substituted alkyl group, or an unsubstituted or substituted alkoxy group; and X and Y are each independently a member selected from the group consisting of alkyl groups and alkoxy groups, is disclosed. This compound is useful as the effective ingredient of a herbicide showing a wide weed-control spectrum even if used in a small amount.

Certain 2-alkanesulfonamido-pyridine derivatives

A substituted pyridinesulfonamide compound or its salt represented by the following formula (I): ##STR1## wherein A is CH; R.sub.1 and R.sub. 2 are each independently a member selected from the group consisting of unsubstituted or substituted alkyl groups, unsubstituted or substituted alkenyl groups, unsubstituted or substituted cycloalkyl groups, and unsubstituted or substituted phenyl groups; and X and Y are each independently a member selected from the group consisting of alkyl groups and alkoxy groups. This compound is an effective ingredient in a herbicide showing a wide weed-control spectrum even when used in a small amount.

Substituted pyridinesulfonamide compound or its salt, process for

A substituted pyridinesulfonamide compound having the formula (I): ##STR1## wherein R.sub.1 is an alkyl group, a haloalkyl group, an alkoxyalkyl group or an alkenyl group, R.sub.2 is a hydrogen atom, an alkyl group, a haloalkyl group, an alkoxyalkyl group or an alkenyl group, R.sub.3 is a hydrogen atom, a halogen atom, an alkyl group, a haloalkyl group, an alkoxy group, an alkylthio group, an alkoxyalkyl group, an alkylamino group or a dialkylamino group, and each of X and Y which are independent from each other, is a halogen atom, an alkyl group, an alkoxy group or a haloalkoxy group, or salt thereof, a preparation thereof, a herbicidal composition containing it and intermediate thereof.

Substituted pyridinesulfonamide compounds, and herbicidal compositions

An aminocarbonyl-substituted pyridinesulfinic acid intermediate for production of an herbicide having formula (V): ##STR1## wherein R.sub.3 and R.sub.4 are selected from the group consisting of hydrogen and alkyl groups, or a salt thereof. The aminocarbonyl-substituted pyridinesulfinic acid or salt thereof is useful as the precursor of aminosulfonyl-substituted pyridinecarbonic acid amide, which in turn is useful as the starting material for agricultural chemicals, medicine, etc.

Mercapto-substituted pyridine compounds, aminocarbonyl-substituted

The present invention relates to an industrially advantageous process for producing 2-amino-4,6-dichloropyrimidine, which comprises reacting 2-amino-4,6-dihydroxypyrimidine or its salt with phosphorus oxychloride at a temperature of from 50.degree. to 100.degree. C. in the presence of a solvent and an acid removing agent. Further, the yield of 2-amino-4,6-dichloropyrimidine can be improved by hydrolyzing 4,6-dichloro-2-pyrimidinylphosphoramidic dichloride produced as a by-product of the chlorination reaction to form 2-amino-4,6-dichloropyrimidine. The 2-amino-4,6-dichloropyrimidine produced by the process of the present invention is useful as an intermediate for medicines and agricultural chemicals.

Process for producing 2-amino-4,6-dichloropyrimidine

Mixtures of herbicidal pyridine sulfonamide compounds of formula: ##STR1## wherein X is a hydrogen atom, a halogen atom, or a methyl group which may be substituted by 1 to 3 halogen atoms, and R is a hydrogen atom or a methyl group, and their salts, with at least one herbicidal compound selected from the group consisting of 2,4-D, Dicamba, Atrazine, Bentazone, Alcachlor, Metolachlor, Propachlor, Pendimethalin, Tridiphane, Cyanazine, Bromoxynil, Acetochlor, etc.

Herbicidal composition

A process for producing 2,6-difluorobenzonitrile comprises reducing a chloro fluorobenzonitrile selected from 3-chloro-2,6-difluorobenzonitrile, 3,5-dichloro-2,6-difluorobenzonitrile or a mixture thereof by hydrogen gas in the presence of a palladium or platinum catalyst at a temperature of 0.degree. to 200.degree. C.

Process for producing 2,6-difluorobenzonitrile

N-benzoyl N'-pyridyloxy phenyl ureas having the formula ##STR1## wherein X represents a halogen atom; R represents a C.sub.1 -C.sub.4 alkyl group and n is 0, 1 or 2 are useful as insecticides.

N-Benzoyl N'-pyridyloxy phenyl urea

N-benzoyl N'-pyridyloxy phenyl ureas having the formula ##STR1## wherein X.sub.1 represents a hydrogen or halogen atom or methyl, trifluoromethyl or nitro group; X.sub.2 represents a hydrogen or halogen atom; X.sub.3, X.sub.4, X.sub.5 and X.sub.6 respectively represent a hydrogen or halogen atom or a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylcarbonyl group, a C.sub.1 -C.sub.4 alkoxycarbonyl group or nitro group; when X.sub.3 and X.sub.6 are both hydrogen atoms, at least one of X.sub.4 and X.sub.5 is a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylcarbonyl group, or a C.sub.1 -C.sub.4 alkoxycarbonyl group; and X.sub.7 represents a hydrogen or halogen atom; and Y represents oxygen or sulfur atom.

N-benzoyl N-pyridyloxy phenyl urea

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Kusatsu, Japan

Shigeo Murai