Yamanouchi Pharmaceutical Company Ltd.

Nippon Flour Mills Co., Ltd

Shigenobu Kadota

Harumitsu Imai

Ken-ichi Suzuki

Shigeru Miyazaki

Takeshi Saito

Kenichi Suzuki

Koji Nagai

Kenji Abe

Fukushi Hirayama

Hirokazu Yamamoto

Hideki Nakashima

Koichi Tanaka

Hiroshi Ogawara

Isao Takahashi

Naoki Yamamoto

Keijiro Uchino

Hidenori Yazawa

Akira Fukuchi

Masaya Iwamoto

Masashi Hiramoto

Sulfated tannins or salts thereof are herein disclosed. These compounds can be prepared by a method which comprises reacting tannin with a sulfonating agent under a basic condition. These compounds show antiviral activity and reverse transcriptase inhibitor, effects and can be used to treat patients infected with a variety of virus such as AIDS virus, herpesvirus, influenza virus or rhinovirus.

Sulfated tannins and their salts

A Q-1047 substance of the general formula (I) and methods of producing the same, which has antioxidant activity and are useful as prophylactic and therapeutic agents for nephritis.

Q-1047 Substances

Novel microorganisms belonging to the genus Micromonospora capable of producing antibiotics YS-02930 K-D, -E or -H represented by formula: ##STR1## wherein R represents a hydrogen atom or a formyl group and a dotted line represents a double bond or a bond shown by: ##STR2## are disclosed. The antibiotics are produced by culturing bacteria belonging to the genus Micromonospora capable of producing at least one antibiotic selected from YS-02930 K-D, -E and -H and, harvesting antibiotic YS-02930 K-D, -E or -H.

Novel microorganisms and a novel process for producing antibiotics

A 7-formylaminocephalosporin compound represented by general formula (I): ##STR1## wherein R.sup.1 represents a carboxy group or an aminocarboxymethyl group ##STR2## R.sup.2 represents a hydrogen atom or a protective group for a carboxy group, and

7-formylaminocephalosporin compounds

Growing community of inventors

Tokyo, Japan

Shigenobu Kadota