Ajinomoto Co., Ltd.

Shigeho Ikeda

Hiroe Yoshii

Minoru Yoshimura

Masayoshi Naruse

Yoshimi Nagano

Takayasu Tsuchida

Yoshio Kawahara

Kiyoshi Tanaka

Yasuhiko Yoshihara

Osamu Tosaka

Chiaki Sano

Yosuke Koyama

Tsutomu Matsuishi

Yutaka Murakami

Sumio Inoue

Hirofumi Hiraga

Hiroshi Fukushi

Takafumi Tosa

Katsunobu Matsushita

Soichiro Asai

Hiromasa Maruyama

Kaetsu Kobayashi

Yoshihiro Takenaka

Kunihiko Akashi

Yayoi Nakamura

Koichi Goto

A fermentative process for producing L-lysine is disclosed. The process is based on growing in a culture medium a mutant strain of the genus Brevibacterium or Corynebacterium (1) capable of producing L-lysine, and (2) having an intensified superoxide dismutase activity.

Fermentation process for producing L-lysine

A feed additive produced by concentrating an aqueous solution containing tryptophan and impurities both originating in the culture broth of a tryptophan-producing microorganism, with the pH of the aqueous solution being maintained in the range of 4 to 6 and the temperature thereof being maintained in the range of 20.degree. to 80.degree. C. during the process of concentrating.

Feed additive containing tryptophan

A process for production of a composition for animal feed, which comprises

Process for the production of a composition for animal feed

A process for producing L-glutamic acid by fermentation is disclosed, which process comprises culturing aerobically in a culture medium a mutant of the genus Brevibacterium or Corynebacterium which has an increased superoxide dismutase activity and is capable of producing L-glutamic acid in the culture medium and recovering the L-glutamic acid. The yield of L-glutamic acid can be increased by using the aforementioned mutants.

Process for producing L-glutamic acid by fermentation

A method for producing L-glutamic acid by fermentation which comprises culturing aerobically in a culture medium a mutant of the genus of Brevibacterium or Corynebaterium which is resistant to Decoyinine or Tubercidin and capable of producing L-glutamic acid, and recovering the L-glutamic acid accumulated in the culture medium.

Method for producing L-glutamic acid by fermentation

Mutants of the genus Brevibacterium or Corynebacterium requiring acetic acid for growth produce L-glutamic acid in an improved yield, especially when they are cultured in an aqueous culture medium containing both saccharide and aliphatic alcohol or acid as the carbon source.

Mutants of the genus Brevibacterium or Coryne-bacterium resistant to a respiratory inhibitor or ADP phosphorylation inhibitor produced L-glutamic acid in a high yield, when they are cultured aerobically in an aqueous culture medium.

Mutants of the genus Bervibacterium or Corynebacterium are given resistance to keto-malonic acid, fluoro-malonic acid, monofluoro-acetic acid or aspartate antagonist and used to produce L-arginine by aerobic fermentation.

Method for production of L-arginine by fermentation

A hydrolyzate of molasses, containing both glucose and fructose, is mixed with calcium hydroxide, and a fructose addition precipitate is recovered. The residual liquor is neutralized, calcium ions are removed, and then the liquor is used as a carbon source for glutamic acid or lysine fermentation. The present method may supply very inexpensive fructose to the market.

Growing community of inventors

Yokohama, Japan

Shigeho Ikeda