Vmware, Inc.

Korea Advanced Institute of Science and Technology

Espressif Systems (shanghai) Co., Ltd.

Huabo Biopharm (shanghai) Co., Ltd.

Shi Chen

Pin Xie

Xiaojin Wu

Biwen Li

Yan Su

Lei Zhang

Sang Yup Lee

Ting Yin

Rui Zhan

Xiangyang Zhu

Zixin Deng

Mingqing Cai

Ling Yu

Ki Jun Jeong

Fengxue Zhang

Liwei Jiang

Xiufen Zhou

The present invention provides an anti-PD-L1/VEGF bispecific antibody and a use thereof. Specifically, the present invention provides a bifunctional antibody, comprising: (a) anti-PD-L1 antibody or element; and (b) an anti-VEGF antibody or element linked to the anti-PD-L1 antibody or element. The bifunctional antibody of the present invention can simultaneously bind to VEGF and PD-L1, thereby exerting a therapeutic effect on VEGF and PD-L1-positive tumor cells (especially malignant tumor cells).

Anti-PD-L1/VEGF bifunctional antibody and use thereof

The present invention relates to an IoT control switch and method based on fingerprint identification permission control, comprising performing user identity and permission verification through fingerprint identification, implementing a MAC layer connectionless communication mechanism between a wire-free fingerprint Wi-Fi IoT switch and a standard Wi-Fi IoT device, and carrying control information for controlling the Wi-Fi IoT device by a privately defined control information element in a unicast packet or broadcast packet without requiring a MAC layer connection; the invention requires little modification, is cost effective to implement, and the data type, manner of acknowledgement, manner of encryption, and different fingerprint security control modes may be freely combined with each other, thereby providing wide applicability. The wire-free fingerprint Wi-Fi IoT switch may complete the translation of control information to the standard Wi-Fi IoT device by sending least number of packets, so as to realize low power consumption control. The wire-free fingerprint Wi-Fi IoT switch may also connect to an internet server via a Wi-Fi access point to perform update and upgrade of firmware, fingerprint feature information list, etc.

Fingerprint identification authority control-based internet of things control switch and method

An example method to provide fault tolerance in a virtualized computing environment with a first host in a first fault domain and a second host in a second fault domain may include determining whether a primary virtualized computing instance and a secondary virtualized computing instance are both in the first fault domain. The secondary virtualized computing instance may be configured as a backup for the primary virtualized computing instance and supported by the first host. The method may further include: in response to determination that the primary virtualized computing instance and secondary virtualized computing instance are both in the first fault domain, selecting, from the second fault domain, the second host based on comparing a resource availability of each of a plurality of hosts that include the first host and the second host; and migrating the secondary virtualized computing instance from the first fault domain to the second fault domain.

Providing fault tolerance in a virtualized computing environment through a swapping approach

Example methods are provided to perform power management for a distributed storage system accessible by a cluster in a virtualized computing environment. The method may comprise determining that a power-off requirement is satisfied for a first host from the cluster. The power-off requirement may be satisfied based on multiple second hosts from the cluster complying with a data placement policy configured for the cluster after the first host is powered off. The method may also comprise based on the data placement policy, placing virtual machine data stored on the first host onto one or more of the multiple second hosts. The method may further comprise migrating one or more virtual machines supported by the first host to one or more of the multiple second hosts; and powering off the first host.

Power management for distributed storage systems

An example method is described to provide fault tolerance in a virtualized computing environment with a first fault domain and a second fault domain. The method may comprise determining whether a first primary virtualized computing instance and a first secondary virtualized computing instance are both in the first fault domain. The method may comprise: in response to determination that the first primary virtualized computing instance and first secondary virtualized computing instance are both in the first fault domain, selecting a second secondary virtualized computing instance from the second fault domain; migrating the first secondary virtualized computing instance from a first host to a second host; and migrating the second secondary virtualized computing instance from the second host to the first host, thereby swapping the first secondary virtualized computing instance in the first fault domain with the second secondary virtualized computing instance in the second fault domain.

An example method is described to provide fault tolerance in a virtualized computing environment with a first fault domain and a second fault domain. The method may comprise determining whether a primary virtualized computing instance and a secondary virtualized computing instance are both in the first fault domain. The secondary virtualized computing instance may be configured as a backup for the primary virtualized computing instance and supported by a first host. The method may further comprise: in response to determination that the primary virtualized computing instance and secondary virtualized computing instance are both in the first fault domain, selecting, from the second fault domain, a second host based on a resource availability of the second host; and migrating the secondary virtualized computing instance from the first host to the second host, thereby migrating the secondary virtualized computing instance from the first fault domain to the second fault domain.

Providing fault tolerance in a virtualized computing environment through a migration approach based on resource availability

The present invention relates to the base sequence of whole genes involved in the biosynthesis of FR-008 polyketides derived fromsp. FR-008. This base sequence comprises genes coding for ketosynthase (KS), acyl transferase (AT), acyl carrier protein (ACP), ketoreductase (KR), dehydratase (DH) and enoyl reductase (ER) domains, and genes coding for modifier enzymes, such as ABC transporter, cytochrome P450 monooxygenase, ferredoxin, thioesterase, sugar synthetic protein, FAD-dependent monooxygenase, 4-amino-4-deoxychorismate (ADC) synthase and ADC lyase. The gene base sequence according to the present invention can be used to increase the productivity of the existing FR-008 polyketides or produce new FR-008 polyketides, through modification of its parts.

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Shanghai, China

Shi Chen