National Science Council

National Science Council of Taiwan

Sheu-Meei Yu

Che-Ming Teng

Chien-Chih Chen

Tian-Shung Wu

Ming-Jai Su

A pharmaceutical composition which possesses vasorelaxing effect of aortic contraction, relaxing effect of tracheal contraction, and antioxidative properties, is disclosed. It contains a pharmaceutical acceptable vehicle and an effective amount of any compound selected from those compounds represented by the following formula: ##STR1## where R.sub.1 represents H, C.sub.1-8 alkyl, or --OCOR, R.sub.2 represents OH, or COO.sup.--, and R represents H, or C.sub.1-8 alkyl.

Thromboxane A2 Receptor antagonism and antioxidant action of

The present invention discloses the method of isolation and purification of the bioactive constituents cinnamophilin from Cinnamomum philippinense (Merr.), the same as Machilus acuminatissima (Hayata). Pharmacological evaluation showed that these compounds possess the activity to inhibit platelet aggregation and to produce relaxing effects of aortic vascular constriction.

Thromboxane A.sub.2 receptor antagonism and antioxidant action of

A method for the treatment of hypertension, arrhythmia, thrombosis or/and atherosclerosis with an effective amount of dicentrine or other alkaloids extracted from Lindera oldhammii (megaphylla) Hemsl.

Growing community of inventors

Taipei, Taiwan

Sheu-Meei Yu