E.i. Dupont De Nemours and Company

Sheryl Wolstenholme

Sharon Jo Keeler

Abigail K Luckring

Michael P Perry

Edwin R Hendrickson

Raymond E Jackson

Linda L Hnatow

Jodie Duke

The present disclosure relates to isolation, identification and application ofstrain AL9:8 which grows on crude oil as the sole carbon source under denitrifying anaerobic conditionsstrain AL9:8 can be used alone or in concert with other microorganisms to improve oil recovery, bioremediation of oil or hydrocarbons in contaminated soil, ground water or bodies of water, such as lakes, rivers or oceans and/or applying to method for promoting oil pipeline maintenance, removing a build up hydrocarbon on the intersurfaces of the pipeline.

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A process was developed for expressing antimicrobial peptides in a recombinant host cell that eliminates host cell toxicity and antimicrobial peptide degradation, as well as providing a process for rapid purification. Fusion proteins comprising a periplasmic targeting signal, cleavage site, and antimicrobial peptides provide the basis for this process which produces antimicrobial peptides that may be used in antimicrobial compositions and articles.

Process for recombinant expression and purification of antimicrobial peptides using periplasmic targeting signals as precipitable hydrophobic tags

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Elkton, MD, United States of America

Sheryl Wolstenholme