Amgen Inc.

Shermeen A Abbas

Wael Mismar

Shaun Robert Devitt

Jessica Hai Liu

Anthony Bitong

Chia-Jung Wu

Mads Schjoth Due

Malak Guirguis

Kenneth G Schalhoub

Rami Saifan

A method of externally sterilizing a drug delivery device utilizing Nitrogen Dioxide (NO2) is provided, including placing the drug delivery device in a sterilization chamber, introducing into the chamber a dose of NO2 having a concentration of between about 2 and 20 milligrams per Liter by applying a vacuum level of between about 10 and 600 Torr and holding the vacuum level for a dwell time of between about 2 and 20 minutes, repeating the step of introducing into the chamber a dose of NO2 for a number of pulses between about 1 and 24, purging the sterilization chamber of at least substantially all of the NO2, and aerating the sterilization chamber.

Method for external sterilization of drug delivery device

Growing community of inventors

Porter Ranch, CA, United States of America

Shermeen A Abbas