Other

Endocon, Inc.

Sherman M Harman

An improved device for subcutaneous implantation of single and plural elongated medicament pellets comprising a single dosage where magazine feeding is not applicable because considerations of sterility and cross-contamination require a fresh needle and obturator for each patient. The device includes a cannula supported at a proximal end thereof by a hub which slides within a tubular barrel, the barrel supporting an obturator which selectively penetrates the cannula to maintain an implanted pellet in position as the cannula is withdrawn. For single pellet dosages, the pellet is carried in the fore part of the cannula, while in the case of multiple pellet dosages, the additional pellets, prior to loading, are carried in open-ended cylindrical tubes engageable with a proximal end of the hub whereby the obturator may be employed to transfer the pellet to the cannula from the sleeve which is discarded. Repositioning of the hub within the sleeve is then accomplished without disengagement of the distal end of the cannula from the tissues of the patient and additional implantations may then be performed.

Cartridge injector for pellet medicaments

A device for administering elongate medicinal pellets in subcutaneous applications. The device includes a hand-held guide element including a hollow barrel enclosing a sliding member having a needle locking means at one end thereof. A disposable cartridge element includes a hollow needle containing a pellet to be implanted and an obturator of length somewhat greater than that of the needle. In use, the cartridge element is engaged at an end thereof with the guide element. The free end of the needle is inserted into the subcutaneous fat of the patient, and the sliding member is moved in an opposite direction to withdraw the needle into the hollow barrel. During this movement, the obturator is maintained relatively stationary by engaging an abutment on the guide element, at one end thereof, the opposite end of the obturator engaging an end of the pellet, so that as the needle is withdrawn, the pellet remains in implanted position. A composite pellet having a core formed of a first ingredient, and a surrounding sleeve formed of a second ingredient is also disclosed, as is a method for making the pellets using a soluble inert core having first and second ingredients coated thereon.

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Ellicott City, MD, United States of America

Sherman M Harman