Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Shenglin Chen

Xin Tian

Chunli Shen

Xiquan Zhang

Chengde Wu

Shuhui Chen

Ting Wang

Lin Zhang

Fei Liu

Jiahu Wu

Yuing Guo

The present application belongs to the field of medicine, and in particular relates to a crystal of a diarylthiohydantoin compound, a preparation method therefor, and use thereof in the preparation of medicaments for treating related diseases which are androgen-mediated.

Crystal of diarylthiohydantoin compound

The present application belongs to the field of medicine. In particular, the present application relates to a diarylthiohydantoin compound as an androgen receptor antagonist or a pharmaceutically acceptable salt thereof, a preparation method of the same, a pharmaceutical composition comprising the compound, and a use thereof in treating a cell proliferative disease mediated by androgen. The compound of the present application has good antagonistic effect on androgen receptor and exhibits excellent antitumor effect.

Diarylthiohydantoin compound as androgen receptor antagonist

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Jiangsu, China

Shenglin Chen