Academia Sinica

Sheng-Yang Wang

Lie-Fen Shyur

Ning-Sun Yang

Yi-Ping Chen

Chia-Chung Hou

Jyh-Horng Wu

Chi-Chang Huang

Pei-wen Hsiao

Feng-Min Lin

Pei-Ling Kang

Show-Jane Sun

The present invention discloses certain diterpenes that can be used to inhibit androgen receptor activity, induce apoptosis and block cell cycle progression of androgen receptor-dependent cells. Androgen receptor has been associated with various diseases such as prostate cancer, androgeneic alopecia, breast cancer, acne etc. Accordingly, the present invention further discloses methods of treating androgen receptor-associated diseases by administering the disclosed diterpenes.

Use certain diterpene compounds in the treatment of androgen receptor-associated diseases

Disclosed are extracts, compositions, and methods for treating cancer and inflammatory disorders. Also disclosed are methods for preparing extracts or compounds for treating the disorders.

Treatment of cancer and inflammatory disorder

Cancer and inflammatory disorder treatment

The present invention provides medicinally active extracts and fractions, and a method for preparing the same by extracting and fractioning constituents from the tissue of plant components of thefamily. These active extracts and fractions are useful for preventing or inhibiting tumor growth.

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Growing community of inventors

Shin-Dian, Taiwan

Sheng-Yang Wang