Alteon Incorporated

Other

Sheng Ding Fang

Dilip R Wagle

Anthony Cerami

Peter C Ulrich

Michael Brines

John J Egan

Qiao-Wen Xie

John Resek

Ihor Terleckyj

In one embodiment, the present invention relates to compounds and compositions including pharmaceutical compositions containing the compounds and associated methods that uncouple sugar-mediated coupling of proteins, lipids, nucleic acids, and other biomaterials, and any combination thereof. In another embodiment, the compositions and associated methods have utility in vivo to reduce the deleterious effects of sugar-mediated coupling processes in an organism, when the organism is exposed to the compound or composition internally, by ingestion, transdermal application, or other means. In yet another embodiment, the compositions and associated methods are useful for the ex-vivo treatment of organs, cells and tissues and external treatment of hair, nails and skin to rejuvenate them by changing deformability and increase the tissue diffusion coefficient. In a further embodiment, the present invention relates to novel compounds and pharmaceutical compositions.

Method and composition for rejuvenating cells, tissues, organs, hair and nails

Method and composition for rejuvenating cells, tissues organs, hair and nails

Provided, among other things, is a compound of the formula:

Cyanomethyl substituted thiazoliums and imidazoliums and treatments of disorders associated with protein aging

Glucose and lipid lowering compounds

Provided are, among other things, lipid-lowering or glucose-lowering methods and compounds, particularly lipid-lowering or glucose-lowering compounds, with an A-B ring structure as follows:

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Mount Kisco, NY, United States of America

Sheng Ding Fang