Repare Therapeutics Inc.

Sheldon N Crane

Vouy Linh Truong

Jean-François Truchon

Stéphane Dorich

Evelyne Dietrich

Bingcan Liu

Janek Szychowski

Lee Fader

Miguel St-Onge

Stéphanie Lanoix

Frédéric Vallée

Cameron Black

Patrick Beaulieu

Robert Papp

Audrey Picard

Alexander Perryman

Cyrus M Lacbay

Kaveh Matinkhoo

Abbas Abdoli

Paul Jones

Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use

Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use as ATR kinase inhibitors

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Pincourt, Canada

Sheldon N Crane