Riverside Research Institute

Sheikh Kaisar Alam

Frederic Louis Lizzi

Ernest Joseph Feleppa

Methods are provided for enhancing the image of brachytherapy seeds implanted in tissue using a transrectal ultrasound apparatus. In a first arrangement the resonance of the seeds is determined and the seeds are insonified using acoustic signals having a resonance frequency of the seeds to cause the seeds to vibrate. The vibrating seeds have enhanced detection using a Doppler ultrasound device. In a second arrangement the acoustic signature of the seeds is determined and used to enhance the imaging of the seeds using a correlation function. In a third arrangement images are taken of the tissue and implanted seeds prior to and during the application of mechanical stress to the tissue. A correlation between the unstressed and stressed tissue can cause enhanced imaging of the seeds.

Ultrasonic method for visualizing brachytheraphy seeds

Improved methods of signal processing for generating estimates of tissue strain are presented. These techniques generally employ the frequency shifting of post-compression spectral data to determine a scaling factor which approximates the applied tissue strain. The scaling factor can be determined by finding the maximum correlation between the frequency shifted post-compression data to the pre-compression data and can also be determined by minimizing the variance of the ratio of such data. Correlation tracking and maximum correlation magnitude techniques for improving the results of elastography are also presented.

Methods for estimating tissue strain

Radiation pulses from a high energy therapeutic ultrasound system are used to stimulate tissue motion by radiation pressure. The tissue motion is monitored using a diagnostic ultrasound system.

Growing community of inventors

Somerset, NJ, United States of America

Sheikh Kaisar Alam