Allergan, Inc.

Sheena K Aurora

Mitchell F Brin

Catherine C Turkel

David W Dodick

Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional follow the pain variable dosage and injection site paradigm is disclosed for optimizing clinical effectiveness of botulinum toxin administration for patients suffering headache, particularly chronic migraine.

Injection paradigm for administration of botulinum toxins

Methods for treating a patient suffering from a medication overuse headache disorder are provided. The methods comprise administering to a patient suffering from a medication overuse disorder a Clostridial toxin. The toxin is administered to the frontalis, corrugator, procerus, occipitalis, temporalis, trapezius and cervical paraspinal muscles of the patient.

Disorders such as headaches can be treated by administration of atoxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional follow the pain variable dosage and injection site paradigm is disclosed for optimizing clinical effectiveness of botulinum toxin administration for patients suffering headache, particularly chronic migraine.

Methods for treating gastric disorders, such as GERD and delayed gastric emptying, by intramuscular administration of atoxin to a head, neck and/or shoulder muscle of a patient with a gastric disorder.

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Seattle, WA, United States of America

Sheena K Aurora