Cedars-sinai Medical Center

University of California

California Institute of Technology

Shawn Wagner

Debiao Li

Louis S Bouchard

Stefan Gloeggler

Jose Agraz

A heterogeneous catalyst composition for para-hydrogen induced polarization includes ligand-capped nanoparticles dispersed in water. The ligand-capped nanoparticles include metal nanoparticles that are surface functionalized with organic ligands, a molecular weight of the organic ligands is no greater than 300 g/mol, and the organic ligands each includes multiple binding moieties as coordinates sites for binding to a nanoparticle surface.

Biologically applicable water-soluble heterogeneous catalysts for para-hydrogen induced polarization

The present invention teaches devices and methods for hyperpolarization by parahydrogen induced polarization. The invention teaches several significant improvements over previous designs, including a heating block, an enhanced solenoid component, and pinch valves and tubing that provide a sterile environment for the sample. All of these advancements can be accomplished while keeping costs to produce the device relatively low.

Devices and methods for parahydrogen induced polarization

Materials suitable for medical and dental implants with magnetic susceptibility matched to surrounding environment to reduce artifacts in nuclear magnetic resonance imaging. Paramagnetic and diamagnetic materials may be added to ceramics and polymer resins to adjust magnetic susceptibility. Other embodiments are described and claimed.

Growing community of inventors

Altadena, CA, United States of America

Shawn Wagner