Hologic, Inc.

Shawn St Pierre

Stephen Grantz

Timothy N Wells

Joseph Vartolone

Joseph A Stand, Iii

John Laviola

Estefania Alvarez

Yuliya Mathis

Brian Stellmach

Lori Fontaine

Michelle Dawn Lyman

Shannon Marie Butler

Richard Gladwin Edwards

Alan W Rego

Kenneth F Defreitas

Henry Landry

Thomas Deyoung

Shawn Hochstetler

Neil Roth

Michelle Lustrino

Thomas E Fisk

Mark Guetersloh

Timothy R Stango

Christophe Fraschini

Christopher Marvel

Susan Harvey

Joseph A Iii Stand

A method of identifying a location of a region of interest within a breast utilizes compressed location coordinates for the region of interest recorded while the breast is under compression during an x-ray imaging procedure such as mammography or tomosynthesis. The compressed location coordinates are converted to uncompressed location coordinates using a mathematical tissue deformation model. The volume and density of the breast affects how the coordinates are translated for use with an ultrasound imaging system. A system including a computing system in communication with an ultrasound imaging system is utilized to perform the method. The resultant predicted location coordinates of the region of interest are used to guide a healthcare provider to potential lesions that are to be examined using ultrasound, where the potential lesions had been previously identified during a screening mammogram.

Systems and methods for identifying regions of interest in multiple imaging modalities

A compression paddle with a plurality of markers is advanced towards a patient's breast which has been positioned on a support platform for an imaging procedure. An initial position of the compression paddle is detected relative to the support platform when a portion of the breast is contacted. An initial marker is identified which is associated with a feature of the breast when the compression paddle is in the initial position. A compression target marker is based at least in part on the initial position and the initial marker.

Breast compression and imaging systems and methods

Methods and systems providing guidance for operation of a biopsy needle based on ultrasonic imaging. Ultrasonic waves are emitted and detected by a ultrasonic transducer to generate image data. A biopsy needle is identified within the generated image data, and the biopsy needle may be in a pre-fire configuration. Based on the identification of the biopsy needle, the methods and systems may determine a predicted location of the biopsy needle based at least in part on biopsy needle properties. The predicted location of the biopsy needle may be the predicated location of the biopsy needle in its post-fire configuration. At least one indicator may be displayed indicating the determined predicted location.

Biopsy needle visualization

A specimen radiography system may include a controller and a cabinet. The cabinet may include an x-ray source, an x-ray detector, and a specimen drawer disposed between the x-ray source and the x-ray detector. The specimen drawer may be automatically positionable along a vertical axis between the x-ray source and the x-ray detector.

Specimen radiography system comprising a cabinet and a specimen drawer positionable by a controller in the cabinet

Systems and methods for locating abnormalities within a breast and generating mappings of structures, such as ducts, within the breast. First imaging data may be acquired for a breast from a first imaging modality and second imaging data for the breast from a second imaging modality. The first imaging data is co-registered with the second imaging data, such that the first imaging data and the second imaging data share a common coordinate space. Based on the second imaging data, a plurality of structures within the breast are mapped to generate a mapping of the plurality of structures. From at least one of the first imaging data or the second imaging data, the abnormality in the breast is located. The mapping of the plurality of structures and the located abnormality in the breast may be concurrently displayed. A statistical analysis of the mapping of the breast structures may also be performed.

Breast mapping and abnormality localization

Methods and system for providing an ultrasound workflow tool that facilitates performing a diagnostic exam, an interventional procedure, and an excision surgery. The ultrasound workflow tool is an application that executes on a computing device, and is used in connection with a wired or wireless ultrasound device.

Breast ultrasound workflow application

Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.

Ultrasound localization system with advanced biopsy site markers

Methods and systems are disclosed for providing guidance for operation of a localization insertion device based on ultrasonic imaging. Ultrasonic waves are emitted and detected by an ultrasonic transducer to generate image data. An introducer for placing a localization wire is identified within the generated image data. Based on the identification of the introducer, the methods and systems may determine a predicted location based at least in part on introducer properties and localization wire properties. The predicted location of the ring of the localization wire may be the predicated location of the localization wire when positioned subcutaneously with the localization insertion device. At least one indicator may be displayed indicating the determined predicted ring location.

Introducer and localization wire visualization

Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses, Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.

Specimen radiography system comprising cabinet and a specimen drawer positionable by a controller in the cabinet

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Marlborough, MA, United States of America

Shawn St Pierre