Agenus Inc.

Shawn Michael Jennings

Nicholas Stuart Wilson

Marc A Van Dijk

David Adam Savitsky

Cornelia Anne Mundt

Olga Ignatovich

Oliver Schon

Jeremy Dale Waight

Benjamin Maxime Morin

Emmanuel Cyrille Pascal Briend

Spencer Campbell

The instant disclosure provides antibodies that specifically bind to LAG-3 (e.g., human LAG-3) and antagonize LAG-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Anti-LAG-3 antibodies and methods of use thereof

Anti-lag-3 antibodies and methods of use thereof

The instant disclosure provides antibodies that specifically bind to CD73 (e.g., human CD73) and antagonize CD73 function. Also provided are anti-CD73 antibodies that further comprise a TGF&#x3b2;-binding moiety or a VEGF-binding moiety. The instant disclosure additionally provides pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Anti-CD73 antibodies and methods of use thereof

Growing community of inventors

Acton, MA, United States of America

Shawn Michael Jennings