Theranos, Inc.

Labrador Diagnostics LLC

F. Hoffmann-la Roche Ag

Geneweave Biosciences, Inc.

Shaunak Roy

Ian Gibbons

Elizabeth A Holmes

Edmond Ku

John K Howard

Chengwang Wang

Timothy Michael Kemp

Shize Daniel Qi

Melissa Takahashi

Chris Todd

Jeff Fenton

Tammy Burd

Keith Moravick

Adam Patrick Vollmer

Bruce Johnson

Anthony Delacruz

Thanh Dang

Uwe Springborn

Ryan C Griswold

Bruce J Richardson

Werner Frei

John Howard

Diego Ariel Rey

Kenneth G Olson

Soni Shukla

Victor H Yee

Nikol De Forest

Malissa Takahashi

Shulin Zeng

Ron Oral

Doran Donnelly

Lance Page

Tim Kemp

Leonardo M Teixeira

Damian S Matthews

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Methods for the detection of analytes in small-volume blood samples

The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Systems and methods of fluidic sample processing

This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.

Fluidic medical devices and uses thereof

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Systems and methods of sample processing and fluid control in a fluidic system

The present invention provides methods of calibrating a fluidic device useful for detecting an analyte of interest in a bodily fluid. The invention also provides methods for assessing the reliability of an assay for an analyte in a bodily fluid with the use of a fluidic device. Another aspect of the invention is a method for performing a trend analysis on the concentration of an analyte in a subject using a fluidic device.

Calibration of fluidic devices

System and methods for analyte detection

The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.

Medical device for analyte monitoring and drug delivery

Detection and quantification of analytes in bodily fluids

Growing community of inventors

San Mateo, CA, United States of America

Shaunak Roy