Warsaw Orthopedic, Inc.

Vanderbilt University

Cook Medical Technologies LLC

Shaun A Tanner

Subhabrata Bhattacharyya

Andrew P Isch

Scott A Guelcher

Jerald E Dumas

Katarzyna Jadwiga Zienkiewicz

Erik Nevarez

Gary Leung

Present inventions present composites of bone particles and polyurethane(s), as well as methods of making such composite and uses thereof. A porous composite comprises a plurality of bone particles; and polyurethanes with which the bone particles are combined. To prepare a porous composite, a composition comprise a plurality of bone particles, polyurethane precursors including polyisocyanate prepolymers and polyols, water and catalyst. A composition is either naturally moldable and/or injectable, or it can be made moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells. Inventive composites have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength for most orthopedic applications.

Bone/polyurethane composites and methods thereof

Growing community of inventors

Charlottesville, VA, United States of America

Shaun A Tanner