Genentech, Inc.

Sharon X Wang

James Q Oeswein

Xanthe M Lam

Rita L Wong

Douglas A Yeung

Robert P Weissburg

John R Smikahl

Boonsri Ongpipattanakul

Zahra Shahrokh

Zehra Shahrokh

A composition is disclosed that comprises a mixture of polypeptides of opposite charge and an excipient selected from the group consisting of arginine, lysine, glutamic acid, sodium dodecyl sulfate, beta-hydroxy cyclodextrin, and beta-cyclodextrin sulfobutyl ether.

Formulated composition

A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of antibody not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.5 to about 6.0, a surfactant and a polyol is described, along with uses for such a formulation.

Antibody formulation

A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.5 to about 6.0, a surfactant and a polyol is described, along with uses for such a formulation.

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San Mateo, CA, United States of America

Sharon X Wang