Biotronik Crm Patent Ag

Sharon Lefkov

Dirk Muessig

Christopher S De Voir

Michael V Orlov

Jie Lian

Hannes Kraetschmer

Garth Garner

Dirk Müssig

David F Hastings

David F Ph D Hastings

The invention refers to a monitoring device for monitoring and analyzing physiological signals. The monitoring device comprises a transthoracic impedance measurement unit and an evaluation unit connected to the transthoracic impedance measurement unit. The transthoracic impedance measurement unit is adapted to conduct a transthoracic impedance measurement and to generate a transthoracic impedance signal representing a measured transthoracic impedance at consecutive points in time. The evaluation unit being configured to process the transthoracic impedance signal received from the transthoracic impedance measurement unit and to thus generate a respiration signal and to generate therefrom an evaluation signal reflecting at least a diurnal pattern of the respiration rate.

Night respiration rate for heart failure monitoring

Heart monitoring apparatus with sensing stage connectable to intracardiac electrode picking up electric potentials and adapted to process electric signals representing a time course of said potentials, a mechanical action detection stage adapted to generate a geometry signal having a time course reflecting heart chamber's geometry change, an evaluation unit connected to sensing stage and impedance measuring stage and adapted to determine a first and second fiducial point in the time course of said potentials and geometry signal, respectively, both fiducial points belonging to same heart cycle, and to determine a measured time delay between said fiducial points. Evaluation unit adapted to repeat said determined time delay to determine plurality of measured time delays and variance thereof or divergence of the statistical properties of cycle times based on said time course of said electric potentials versus cycle times based on said time course reflecting a change of a heart chamber's geometry.

Heart monitoring apparatus

Implantable medical device with an impedance determination unit with constant current/voltage source having current feed terminals connected to electrodes for intracorporal placement which generates measuring current pulses having constant current/voltage, for causing a current through a body via intracorporally placed electrodes, a measuring unit for measuring voltage/current strength of voltage/current fed through body, an impedance value determination unit connected to the current/voltage source and adapted to determine an impedance value for each measuring current pulse, and an impedance measuring control and evaluation unit connected to the impedance determination unit which controls the unit and evaluates a sequence of consecutive impedance values, the impedance determination unit further adapted to determine at least intrathoracic and intracardiac impedance values for same period of time, the intrathoracic values sampled with a lower sampling rate than the intracardiac values.

Implantable medical devices evaluating thorax impedance

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Portland, OR, United States of America

Sharon Lefkov