Celator Pharmaceuticals, Inc.

Sharon Johnstone

Lawrence D Mayer

Paul Tardi

Marcel B Bally

Murray Webb

Troy Harasym

Sheela Abraham

Steven M Ansell

Nanoparticulate formulations for delivery of taxane conjugate prodrug formed from a taxane coupled to a hydrophobic moiety through a glycolate linker are described.

Taxane delivery system

Compositions which comprise an anthracycline agent, and a cytidine analog are encapsulated in liposomal carriers. The preferred anthracycline agent is selected from the group of daunorubicin, doxorubicin, and idarubicin, while the preferred cytidine analog is selected from the group of cytarabine, gemcitabine, or 5-azacytidine. The combination of the anthracycline agent and cytidine analog encapsulated in said liposomal carriers are useful in achieving a drug retention and a sustained drug release for each therapeutic agent.

Liposomal formulations of anthracycline agents and cytidine analogs

This invention relates to encapsulation of drugs and other agents into liposomes.

Liposome loading with metal ions

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Vancouver, Canada

Sharon Johnstone