Arla Foods Amba

University of Illinois

Abbott Laboratories Corporation

Sharon Donovan

Sarah S Comstock

Peter Langborg Wejse

Anne Staudt Kvistgaard

Marcia H Monaco Siegel

Gregory T Bleck

Matthew B Wheeler

Rachael Buck

Joseph P Schaller

Geralyn O Duska-McEwen

Marcia Monaco-Siegel

Marcia Monaco-Seigel

Geralyn Duska-Mcewen

Marcia H Siegel

The disclosed invention provides mammalian milk osteopontin and/or an active truncation or active peptide thereof for improving immune responsiveness to an infectious disease in a mammal, for example a human subject, as well as enhancing the efficacy of vaccination for the prophylactic or therapeutic treatment of an infectious disease in mammals, such as humans. The invention further provides a vaccine system, for use in the prophylactic or therapeutic treatment of an infectious disease in a mammal, comprising a vaccine and a mammalian milk osteopontin and/or an active truncation or active peptide thereof for oral administration to a mammal, as well as methods of enhancing immune resistance to an infectious disease in a mammal by administration of a vaccine and a mammalian milk osteopontin and/or an active truncation thereof.

Mammalian milk osteopontin for enhancing immune responsiveness

Disclosed is a nutritional composition for use in modulating or reducing inflammation in an adult or elderly individual in need thereof. In some aspects, the nutritional composition comprises a neutral human milk oligosaccharide.

Nutritional formulations using human milk oligosaccharides for modulating inflammation

The present invention relates to animals that express exogenous growth factors in their milk, and in particular to pigs that express exogenous IGF-I in their milk. The present invention also relates to methods for increasing piglet weight gain and intestinal lactase activity. The present invention thus provides a method of facilitating piglet development and decreasing piglet mortality.

Mammals expressing IGF-1 and alpha-lactalbumin in their milk

Ungulates expressing exogenous IGF-I in their milk

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Champaign, IL, United States of America

Sharon Donovan