Nestec S.a.

Sony Group Corporation

Sony Corporation

Biora Therapeutics, Inc.

Progenity, Inc.

SociÉtÉ Des Produits NestlÉ S.a.

Prometheus Laboratories Inc.

Sony Corporation of America

Pierian Holdings, Inc.

Prometheus Biosciences, Inc.

Enumera Molecular, Inc.

Other

Katholieke Universiteit Leuven

Monogram Biosciences, Inc.

Prometheus Biosiences, Inc.

Sharat Singh

Tracy Matray

Phillip Kim

Mitchell Lawrence Jones

Christopher Loren Wahl

Xinjun Liu

Shui Long Wang

Michael VanBrunt

Harry Stylli

Jeanne Harvey

Linda Ohrmund

Limin Liu

Robert Barham

Fred Princen

Steven Lockton

Bruce P Neri

Nicholas Chi-Kwan Ling

Fabiyola Selvaraj

Stefan Westin

Scott Hauenstein

Anjali Jain

Matthew Sekedat

Ronald David Beaubien, Jr

Belen Ybarrondo

Jeff Perry

Jeffrey Buis

C Frederick Battrell

Amin R Mazloom

Venkateswarlu Kondragunta

Tani Lee

Hua Gong

Shui-Long Wang

Richard Kirkland

Pankaj Oberoi

Kevin Howe

Natalie Mae Jameson-Kiesling

Arana Perera

Chandni Jain

Nicholas Hoe

Jared Salbato

Steve Lockton

Matthew L Cooper

Po-Ying Chan-Hui

Mark Sasha Drlik

Robert Stanford Magyar

Rajiv Dua

Hossein Salimi-Moosavi

Richard Giulio Del Mastro

Ali Mukherjee

Aaron Olafur Laurence Philippsen

Nicholas David Allan

Yining Shi

Sailaja Pidaparthi

Lyndal Hesterberg

Lisa Croner

Derren Barken

Thomas Stockfisch

Severine Vermeire

John Mccutcheon

Michael Vanbrunt

Melissa Jackson

Christopher Boyce

Eriko Matsui

Karen A F Copeland

Frederick A Fletcher

Ryan Paul McGuinness

Severine Vermiere

Marc Ferrante

Mohammad Abbasi

Kelly D Hester

Leonard Eggleston

Allison Luo

Dunrui Wang

Uining Shi

Katherine Drake

Kevin David Howe

Jr Ronald David Beaubien

Po-Ying Chan-hui

Lisa J Croner

Aruna Perera

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, M, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

Ultra bright dimeric or polymeric dyes with spacing linker groups

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): or a stereoisomer, tantomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, L, L, L, L, M, M, q, w, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

Polymeric dyes with linker groups comprising deoxyribose

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I), or a stereoisomer, tautomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, M, M, m and n are as defined herein. Methods associated with preparation and use of such compounds is also provided.

Polymeric tandem dyes with linker groups

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, M, M, m and n are as defined herein. Methods associated with preparation and use of such compounds is also provided.

This disclosure features methods and compositions for treating inflammatory disorders or conditions that arise in a tissue originating from the endoderm using an immune modulator.

Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine

This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a JAK or other kinase inhibitor.

Treatment of a disease of the gastrointestinal tract with a JAK or other kinase inhibitor

This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunosuppressant.

Treatment of a disease of the gastrointestinal tract with an immunosuppressant

Compounds useful as biologically active compounds are disclosed. The compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, wherein R, R, R, L, L, L, L, M and n are as defined herein. Methods associated with preparation and use of such compounds is also provided.

Programmable polymeric drugs

The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

Gastrointestinal tract detection methods, devices and systems

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): (I) or a stereoisomer, tautomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, L, L, L, L, M, M2, q, w, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (II): or a stereoisomer, tautomer or salt thereof, wherein R, R, R, R, R, L, L, L, L, M, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

Ultra bright dimeric or polymeric dyes

Compositions and methods, systems, and kits for detecting and quantifying variations in numbers of molecules, particularly variations in gene dosage, e.g., due to gene duplication, or to variations from the normal euploid complement of chromosomes, e.g., trisomy of one or more chromosomes that are normally found in diploid pairs, without digital sequencing.

Methods, systems, and compositions for counting nucleic acid molecules

Compositions comprising fluorescent or colored dyes and methods of using the same in combination with divalent metal salts to analyze samples are disclosed.

Use of divalent metals for enhancement of fluorescent signals

Growing community of inventors

Rancho Santa Fe, CA, United States of America

Sharat Singh