Nomadics, Inc.

Oklahoma State University

Shaopeng Wang

Brent Everett Little

Nicholas Alexander Kotov

Frederick Gorr Johnson

Wei Chen

Edward Thomas Knobbe

Akhilesh Ramachandran

Sarah Westcott

David Wesley Goad

Jun Zhang

The current invention provides methods for detecting trace analytes in solution or suspension using coupled micro-ring resonators. The methods of the current invention determine the presence and concentration of the target analytes in real time by exposing the micro-ring resonator to the analyte and determining the resulting rate of change of resonance wavelength experienced by a sensing micro-ring resonator as compared to a reference micro-ring resonator.

Integrated optical resonator device for measuring chemical and biological analyte concentrations

The presently claimed and disclosed inventions relate, in general, to methods of radiation dosimetry and imaging using scintillation luminescence. More particularly, materials having a scintillation luminescence response to radiation that varies with total radiation dose received can be used for dosimetry monitoring, including, but not limited to nanoparticles for in vivo, real-time dosimetry. Energy-transfer nanocomposite materials as well as methods of making and using such materials in various applications including, but not limited to, in vivo radiation dosimetry and imaging, are disclosed. More particularly, the presently claimed and disclosed inventions relate to nanoparticle scintillation luminescence particles encapsulated in hosts of the general formula BaFX and BaFX:Euwhere X=Cl, Br and I.

Energy-transfer nanocomposite materials and methods of making and using same

A cell growth matrix for optimizing 3D organization nutrient delivery, controlling release of differentiation factors and facilitating attachment of cells to a scaffold Colloidal crystals and inverted colloidal crystals are used to form an ordered structure for use as a scaffold for tissue engineering. The porosity of the cell growth matrix may be modified by the selection of particles of appropriate diameter. Further, the surface of colloidal crystals can be easily modified to accommodate many organic species including biomolecules. Layer-by-layer materials are used for tissue engineering to control cell development by using sequential layering of bioactive species wherein the number and order of LBL layers deposited between layers containing a particular protein are controlled. LBL may also be used for timed release of bioactive species. Increased control differentiation factors release and control of cell attachments to the scaffold are achieved to better mimic natural tissue development.

3D tissue constructs on the basis of colloidal crystals surface modified by sequential layering

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Stillwater, OK, United States of America

Shaopeng Wang