Cardiac Pacemakers, Inc.

Boston Scientific Scimed, Inc.

Caridac Pacemakers, Inc.

Shantha Arcot-Krishnamurthy

Allan Charles Shuros

Barun Maskara

Shibaji Shome

Pramodsingh Hirasingh Thakur

Sunipa Saha

David J Ternes

Jason J Hamann

Juan Gabriel Hincapie Ordonez

Yinghong Yu

Jeffrey E Stahmann

Jiang Ding

Stephen B Ruble

Donald Lee Hopper

Eric A Mokelke

Michael J Stucky

Joseph M Pastore

Robert Shipley

Yi Zhang

Yanting Dong

Gerrard Merrill Carlson

Kent Lee

Scott A Meyer

Christopher A Hartemink

John R Zielinski

Bruce H KenKnight

Quan Ni

Dan Li

Brian D Soltis

Stephen John Hahn

Douglas R Daum

Lili Liu

Jonathan T Kwok

Craig Michael Stolen

Kenneth C Beck

Guy Alvarez

Zheng Lin

David L Whitehouse

John D Hatlestad

Rodney W Salo

Kevin John Stalsberg

Tamara Colette Baynham

Xuan K Wei

Gary Thomas Seim

Scott R Vanderlinde

Jacob I Laughner

Joseph Walker

Jihong Qu

Cheng Zhang

Chris Hartemink

An anatomical mapping system including a plurality of mapping electrodes disposed in or near an anatomical structure and configured to detect activation signals of physiological activity, each of the plurality of mapping electrodes having an electrode location, and a processing system associated with the plurality of mapping electrodes, and configured to record the detected activation signals and associate one of the plurality of mapping electrodes with each recorded activation signal. The processing system further configured to determine a dominant frequency at each electrode location, and determine a wavefront vector at each electrode location based on a difference between the dominant frequency at a first electrode location and the dominant frequency at neighboring electrode locations.

Estimating the prevalence of activation patterns in data segments during electrophysiology mapping

A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure, each of the plurality of mapping electrodes having an electrode location. A vector field map which represents a direction of propagation of the activation signals at each electrode location is generated to identify a signature pattern and a location in the vector field map according to at least one vector field template. A target location of the identified signature pattern is identified according to a corresponding electrode location.

Representation and identification of activity patterns during electro-physiology mapping using vector fields

A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on a signal parameter of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.

Real-time feedback for electrode contact during mapping

An implantable pacing device for delivering ventricular pacing may be configured to intermittently and variably reduce the AV delay interval used in an atrial triggered pacing mode in a manner that simulates exercise. The device may be programmed to intermittently switch to and from a variably shortened AV delay mode according to defined entry and exit conditions.

Variable shortening of AV delay for treatment of cardiac disease

Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The plurality of electrodes may include a first pair of electrodes, a second pair of electrodes, a third pair of electrodes and a fourth pair of electrodes. The mapping medical device may further include a processor, wherein the processor may be configured to determine a first latency between the first pair of electrodes, determine a second latency between the second pair of electrodes, determine a third latency between the third pair of electrodes, determine a fourth latency between the fourth pair of electrodes, and determine a target signal by interpolating the first latency, the second latency, the third latency and the fourth latency.

Cardiac mapping using latency interpolation

A medical apparatus comprising an implantable lead and a stylet configured for stimulation of a target region of a patient's nervous system is described. The lead includes a generally tubular lead body, a conductor, and an electrode assembly. The generally tubular lead body has a stylet lumen and a conductor lumen extending through the proximal and distal ends of the lead body. The conductor is enclosed within the conductor lumen. The electrode assembly extends from the distal end of the lead body. The electrode assembly includes a flexible polymeric carrier and an electrode on the carrier and electrically coupled to the conductor. The stylet is sized and shaped to be receivable within the stylet lumen and configured to stiffen and support the lead body. The distal portion of the stylet includes a bend having a predetermined angle of incidence relative to the proximal portion of the stylet.

Apparatus for baroreceptor stimulation therapy

Implanted electrodes can be used to deliver electrical stimulation signals to areas near blood vessels, nerves, or other internal body locations. In an example, an electrode can be implanted in a cervical location and can be used to measure dimensional changes in an artery using impedance plethysmography. Measured artery dimensional changes can be used to determine one or more physiological parameters associated with a patient's health status, such as pulse transit time, relative pulse pressure, or aterial compliance, among others. These parameters can be used to monitor a patient health status or to modulate a patient's therapy, among other uses. In some examples, an electrode configured to deliver an electrostimulation signal to nerve tissue can be used to provide non-neurostimulating electrical stimulation plethysmography signals near a blood vessel.

Method and apparatus for determination of physiological parameters using cervical impedance

An electrode structure for an implantable stimulation lead for use in stimulating a target nerve structure within a patient includes a flexible backing defined by a major dimension extending in a direction of a first axis, and a minor dimension extending generally orthogonal to the first axis. The electrode structure also includes a plurality of electrodes coupled to the backing.

Multi-electrode lead with backing for mecho/baroreceptor stimulation

A system and method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure. Patterns among the sensed activation signals are identified based on a similarity measure generated between each unique pair of identified patterns which are classified into groups based on a correlation between the corresponding pairs of similarity measures. A characteristic representation is determined for each group of similarity measures and displayed as a summary plot of the characteristic representations.

A neurostimulation system includes a neural stimulation lead having a proximal portion and a distal portion and including a plurality of electrodes along the distal portion. The plurality of electrodes are configured for positioning proximate a portion of the autonomic nervous system. A neural stimulation circuit, coupled to the plurality of electrodes, delivers neural stimulation pulses to the plurality of electrodes. A processor and controller is configured to control the neural stimulation circuit to deliver first neural stimulation pulses to each of a plurality of electrode configurations. Each electrode configuration includes one or more of the plurality of electrodes. The processor and controller is further configured to receive information related to motor fiber activity that is induced in response to delivery of the first neural stimulation pulses to each of the plurality of electrode configurations and to identify the electrode configurations that induce the motor fiber activity.

Automatic selection of lead configuration for a neural stimulation lead

Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The catheter shaft may be coupled to a processor. The processor may be capable of collecting a first set of signals from a first location, collecting a second set of signals from a second location, characterizing the first set of signals over a first time period, characterizing the second set of signals over a second time period, comparing the first set of signals to the second set of signals and matching a first signal from the first set of signals with a second signal from the second set of signals.

Medical device for high resolution mapping using localized matching

A method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure, identifying at least one of the electrodes not in direct contact with the anatomical structure, and adjusting the activation signals sensed by each of the plurality of electrodes based on the activation signals sensed by the identified at least one of the electrodes not in direct contact with the anatomical structure.

Suppression of global activation signals during anatomical mapping

A system and method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure. A most recent intrinsic event at a selected time is determined based on the sensed activation signals and a persistent display of relevant characteristics is generated based on the sensed activation signals of the most recent intrinsic event. The persistent display is updated upon detection of a subsequent intrinsic event.

Persistent display of nearest beat characteristics during real-time or play-back electrophysiology data visualization

An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Enhanced activation onset time optimization by similarity based pattern matching

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Vadnais Heights, MN, United States of America

Shantha Arcot-Krishnamurthy